β-Chlorolactic acid
β-Chlorolactic acid structure
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Common Name | β-Chlorolactic acid | ||
|---|---|---|---|---|
| CAS Number | 1713-85-5 | Molecular Weight | 124.52300 | |
| Density | 1.519g/cm3 | Boiling Point | 259.5ºC at 760mmHg | |
| Molecular Formula | C3H5ClO3 | Melting Point | 77 °C (lit.) | |
| MSDS | Chinese USA | Flash Point | 110.8ºC | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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The effect of the isomers of alpha-cholorohydrin and racemic beta-chlorolactate on the rat kidney.
Chem. Biol. Interact. 41(1) , 95-104, (1982) The (R)- and (S)-isomers of the male antifertility agent alpha-chlorohydrin have been synthesized. When administered to rats, the (R)-isomer induced a period of diuresis and glucosuria, whereas the (S)-isomer, which possesses the antifertility activity, had n... |
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Oxidative metabolic activity of boar spermatozoa: a system for assessing anti-glycolytic activity of potential inhibitors in vitro.
Reprod. Fertil. Dev. 1(4) , 357-67, (1989) The oxidative metabolic capability of mature boar spermatozoa has been determined in vitro. The high rate of oxidation of fructose, glucose, glycerol, glycerol-3-phosphate and lactate to CO2 and the optimization of incubation conditions indicates that these c... |
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The renal toxicity of (R)-3-chlorolactate in the rat.
Chem. Biol. Interact. 62(2) , 157-66, (1987) The renal toxicity of (R,S)-3-chlorolactate has been shown to be due to the (R)-isomer which, when administered to rats, induces diuresis and glucosuria. The metabolic activity of isolated tubule cells, prepared from rat kidney, was inhibited by (R)-3-chlorol... |
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Is the nephrotoxicity of (R)-3-chlorolactate in the rat caused by 3-chloropyruvate?
Xenobiotica 18(12) , 1389-99, (1988) 1. When (R, S)-[3-36 Cl]chlorolactate was administered to male rats, two radioactive constituents were excreted in the urine. These were identified as 36Cl- and [3-36 Cl]chlorolactate which was subsequently shown to be essentially the (S)-isomer. 2. Analysis ... |
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Immunotoxic effect of beta-chlorolactic acid on murine splenocyte and peritoneal macrophage function in vitro.
Toxicology 210(2-3) , 175-87, (2005) Beta-chlorolactic acid is a major intermediate of 3-monochloro-1,2-propanediol (MCPD) in mammalian species, which a well-known by-product of acid-hydrolyzed soy sauce during its manufacturing process. beta-Chlorolactic acid has not been studied on immunotoxic... |