(Z)-4-Amino-4-oxobut-2-enoic acid

(Z)-4-Amino-4-oxobut-2-enoic acid Structure
(Z)-4-Amino-4-oxobut-2-enoic acid structure
Common Name (Z)-4-Amino-4-oxobut-2-enoic acid
CAS Number 557-24-4 Molecular Weight 115.08700
Density 1.376g/cm3 Boiling Point 408.6ºC at 760mmHg
Molecular Formula C4H5NO3 Melting Point 158-161 °C(lit.)
MSDS Chinese USA Flash Point 200.9ºC
Symbol GHS07
GHS07
Signal Word Warning

Hapten synthesis and development of a competitive indirect enzyme-linked immunosorbent assay for acrylamide in food samples.

J. Agric. Food Chem. 62(29) , 7078-84, (2014)

The high level of acrylamide in widely consumed processed foods poses a potentially significant risk to human health, which has led to an increasing demand for rapid, simple, and selective analytical methods. In the present work, several haptens for acrylamid...

N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids.

Bioorg. Med. Chem. 16 , 560-8, (2008)

N-Phenyl and N-phenylalkyl maleimides (alkyl chain=(CH(2))n; n=0-4) and their respective open derivatives (maleamic acids) were evaluated against Candida spp. with the microbroth dilution method following the guidelines of CLSI (formely NCCLS). MIC values of ...

Selective adsorption of D- and L-phenylalanine on molecularly-imprinted polymerized organogels formed using polymerizable gelator N-octadecyl maleamic acid.

J. Sep. Sci. 31(21) , 3782-7, (2008)

The polymerizable gelator N-octadecyl maleamic acid (ODMA) can self-assemble in selected polymerizable organic solvents, such as 2-hydroxyethyl methacrylate (HEMA) and methylacrylic acid (MAA) to form thermally stable polymerizable organogels. A mixture consi...

Study of graft copolymerization of N-maleamic acid-chitosan and butyl acrylate by gamma-ray irradiation.

Int. J. Biol. Macromol. 36(1-2) , 98-102, (2005)

N-maleamic acid-chitosan was synthesized and characterized by Fourier transform infrared spectra analysis (FT-IR) and 1H NMR. The graft copolymerization of N-maleamic acid-chitosan and butyl acrylate (BA) in acetic acid aqueous solution was investigated, usin...

Structure and catalytic mechanism of nicotinate (vitamin B3) degradative enzyme maleamate amidohydrolase from Bordetella bronchiseptica RB50.

Biochemistry 51(1) , 545-54, (2012)

The penultimate reaction in the oxidative degradation of nicotinate (vitamin B(3)) to fumarate in several species of aerobic bacteria is the hydrolytic deamination of maleamate to maleate, catalyzed by maleamate amidohydrolase (NicF). Although it has been con...

PEGylation of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) results in decreased uptake into rats and human liver.

J. Pharm. Pharmacol. 62(8) , 985-94, (2010)

Our aim was to investigate the effect of PEGylation on the uptake of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) into rat liver, kidney and spleen, and human liver.Copolymer of polyethyleneglycol allylmethylether and maleamic acid sodium s...

Prodrugs of acyclovir--a computational approach.

Chem. Biol. Drug Des. 79(5) , 819-34, (2012)

Density functional theory calculation results demonstrated that the efficiency of the acid-catalyzed hydrolysis of Kirby's acid amides 1-15 is strongly dependent on the substitution on the C-C double bond and the nature of the amide N-alkyl group. Further, th...

The bacterial oxidation of nicotinic acid.

J. Biol. Chem. 228(2) , 923-45, (1957)

Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation.

Sci. Rep. 2 , 377, (2012)

Nicotine is an important chemical compound in nature that has been regarded as an environmental toxicant causing various preventable diseases. Several bacterial species are adapted to decompose this heterocyclic compound, including Pseudomonas and Arthrobacte...

Iron(II)-dependent dioxygenase and N-formylamide deformylase catalyze the reactions from 5-hydroxy-2-pyridone to maleamate.

Sci. Rep. 3 , 3235, (2013)

5-Hydroxy-2-pyridone (2,5-DHP) is a central metabolic intermediate in catabolism of many pyridine derivatives, and has been suggested as a potential carcinogen. 2,5-DHP is frequently transformed to N-formylmaleamic acid (NFM) by a 2,5-DHP dioxygenase. Three h...