4-Chlorobenzenesulfonamide
4-Chlorobenzenesulfonamide structure
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Common Name | 4-Chlorobenzenesulfonamide | ||
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| CAS Number | 98-64-6 | Molecular Weight | 191.635 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 342.2±44.0 °C at 760 mmHg | |
| Molecular Formula | C6H6ClNO2S | Melting Point | 140-144 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 160.8±28.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Determination of the content of 2-chlorobenzenesulphonamide and bis(p-chlorophenyl) sulphone in 4-chlorobenzenesulphonamide.
J. Chromatogr. A. 333(1) , 253-5, (1985)
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Novel use of chemical shift in NMR as molecular descriptor: a first report on modeling carbonic anhydrase inhibitory activity and related parameters.
Bioorg. Med. Chem. Lett. 15 , 931-6, (2005) A novel use of NMR chemical shift of the SO(2)NH(2) protons (in dioxane as solvent) as a molecular descriptor is described for modeling the inhibition constant for benzene sulfonamides against the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1). The methodolo... |
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Correlation analyses on binding affinity of substituted benzenesulfonamides with carbonic anhydrase using ab initio MO calculations on their complex structures (II).
Bioorg. Med. Chem. Lett. 21 , 141-4, (2011) We proposed a novel QSAR (quantitative structure-activity relationship) procedure called LERE (linear expression by representative energy terms)-QSAR involving molecular calculations such as ab initio fragment molecular orbital and generalized Born/surface ar... |
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Comparative anticonvulsant activity of 4-chlorobenzenesulfonamide and prototype antiepileptic drugs in rodents.
Epilepsia 31(4) , 474-9, (1990) The anticonvulsant and toxic properties of 4-chlorobenzenesulfonamide (ADD 55051) were compared with phenytoin (PHT), phenobarbital (PB), ethosuximide (ESM), and valproate (VPA). These compounds were evaluated in mice and rats using well-standardized anti-con... |