Primidone
Primidone structure
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Common Name | Primidone | ||
|---|---|---|---|---|
| CAS Number | 125-33-7 | Molecular Weight | 218.25200 | |
| Density | 1.138g/cm3 | Boiling Point | 520.7ºC at 760mmHg | |
| Molecular Formula | C12H14N2O2 | Melting Point | 281-282°C | |
| MSDS | Chinese USA | Flash Point | 228.2ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Optimized removal of dissolved organic carbon and trace organic contaminants during combined ozonation and artificial groundwater recharge.
Water Res. 46(18) , 6059-68, (2012) Pilot scale experiments using an 8 g/h ozonation unit and a 1.4 m(2) slow sand filter have demonstrated that the combination of ozonation and artificial groundwater recharge is suitable for efficient reduction of bulk and trace organics. The biodegradation of... |
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Carrier Mediated Distribution System (CAMDIS): a new approach for the measurement of octanol/water distribution coefficients.
Eur. J. Pharm. Sci. 68 , 68-77, (2015) Here we present a miniaturized assay, referred to as Carrier-Mediated Distribution System (CAMDIS) for fast and reliable measurement of octanol/water distribution coefficients, log D(oct). By introducing a filter support for octanol, phase separation from wat... |
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How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Epilepsia 53 Suppl 8 , 3-11, (2012) Phenobarbital has been in clinical use as an antiepileptic drug (AED) since 1912. The initial clinical success of phenobarbital and other barbiturates affected the design of subsequent AEDs (e.g., phenytoin, primidone, ethosuximide), developed between 1938 an... |
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Effect of transpiration on plant accumulation and translocation of PPCP/EDCs.
Environ. Pollut. 198 , 144-53, (2015) The reuse of treated wastewater for agricultural irrigation in arid and hot climates where plant transpiration is high may affect plant accumulation of pharmaceutical and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs). In this study,... |
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Evaluation of the matrix effect of different sample matrices for 33 pharmaceuticals by post-column infusion.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1000 , 84-94, (2015) Matrix effects that occur during quantitative measurement by liquid chromatography mass spectrometry specifically when using electrospray ionization are a widely recognized phenomenon. Sample matrix compounds affect the ionization process of the target analyt... |
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Is primidone the drug of choice for epileptic patients with QT-prolongation? A comprehensive analysis of literature.
Seizure 15(1) , 64-6, (2006) Sudden unexplained/unexpected death (SUDEP) in epilepsy is a major cause of death accounting for 7-17% of the mortality among epileptic patients. Prolongation of QT-interval has been issued as a major mechanism in SUDEP since it is associated with fatal cardi... |
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How best to address these common movement disorders.
J. Fam. Pract. 60(12) , 721-5, (2011)
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Pharmacologic management of essential tremor.
Can. Fam. Physician 56(3) , 250-2, (2010)
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[Barbiturate rheumatism as a complication of essential tremor].
Rev. Neurol. 49(6) , 332-3, (2009)
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Anticonvulsant drugs in alcohol withdrawal: use of phenytoin, primidone, carbamazepine, valproic acid, and the sedative anticonvulsants.
Am. J. Hosp. Pharm. 38(8) , 1138-43, (1981) The evidence for the efficacy of anticonvulsant drugs in the control of seizures during alcohol withdrawal is examined. The literature on the use of anticonvulsants to control anxiety, irritability, tension, and other symptoms of abstinence syndrome is review... |