Prolactin, Human Pituitary, Iodination Grade

Prolactin, Human Pituitary, Iodination Grade Structure
Prolactin, Human Pituitary, Iodination Grade structure
Common Name Prolactin, Human Pituitary, Iodination Grade
CAS Number 9002-62-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation.

Genes Dev. 28(9) , 983-94, (2014)

In most tissues, the prevailing view is that stem cell (SC) niches are generated by signals from within the nearby tissue environment. Here, we define genetic changes altered in hair follicle (HF) SCs in mice treated with a potent SC activator, cyclosporine A...

Inclusion of endogenous hormone levels in risk prediction models of postmenopausal breast cancer.

J. Clin. Oncol. 32(28) , 3111-7, (2014)

Endogenous hormones are risk factors for postmenopausal breast cancer, and their measurement may improve our ability to identify high-risk women. Therefore, we evaluated whether inclusion of plasma estradiol, estrone, estrone sulfate, testosterone, dehydroepi...

Longer anogenital distance is associated with higher testosterone levels in women: a cross-sectional study.

BJOG 121(11) , 1359-64, (2014)

Animal models have suggested that anogenital distance (AGD) at birth reflects androgen levels during in utero development and predicts adult AGD. A recent study showed an association between perineal length and androgen levels in men, suggesting that serum te...

[Specifics of hormonal and energy balance in patients with hyperplasia and endometrial neoplasia with metabolic syndrome in the background].

Vopr. Onkol. 59(1) , 65-71, (2013)

We conducted a comparative investigation of the hormonal status (LH, FSH, estradiol, progesterone, testosterone, prolactin, SHBG), energy status (leptin, ghrelin, insulin), and carbohydrate and lipid metabolism in patients with endometrial hyperplasia and neo...

Anti-metastatic outcome of isoform-specific prolactin receptor targeting in breast cancer

Cancer Lett. 366 , 84-92, (2015)

• The work establishes a crucial role for the long prolactin receptor in metastatic spread of breast cancer. • The spice-modulating agent has potential as a well-tolerated cancer therapeutic. • The principle of isoform-specific knockdown can be applied to mul...

The effect of the Taq1A variant in the dopamine D₂ receptor gene and common CYP2D6 alleles on prolactin levels in risperidone-treated boys.

Pharmacogenet. Genomics 23(9) , 487-93, (2013)

To investigate the effect of the Taq1A variant in the Dopamine D2 receptor gene (DRD2) and common functional genetic variants in the cytochrome P450 2D6 gene (CYP2D6) on prolactin levels in risperidone-treated boys with autism spectrum disorders and disruptiv...

Differential expression and regulation of Tdo2 during mouse decidualization.

J. Endocrinol. 220(1) , 73-83, (2014)

Tryptophan 2,3-dioxygenase (Tdo2) is a rate-limiting enzyme which directs the conversion of tryptophan to kynurenine. The aim of this study was to examine the expression and regulation of Tdo2 in mouse uterus during decidualization. Tdo2 mRNA was mainly expre...

Gonadotropinoma presenting as a case of pseudo-ovarian failure changing to macroprolactinoma.

Clin. Exp. Obstet. Gynecol. 40(2) , 295-6, (2013)

To present the first gonadotropinoma presenting as pseudo-menopause in a teenager.Human menopausal gonadotropins (hMG) were given to a 37-year-old woman whose hypergonadotropic amenorrhea with estrogen deficiency as a teenager was changed to hypogonadotropic ...

Impact of subdomain D1 of the short form S1b of the human prolactin receptor on its inhibitory action on the function of the long form of the receptor induced by prolactin.

Biochim. Biophys. Acta 1840(7) , 2272-80, (2014)

Long-form (LF) homodimers of the human prolactin receptor (PRLR) mediate prolactin's diverse actions. Short form S1b inhibits the LF function through heterodimerization. Reduced S1b/LF-ratio in breast cancer could contribute to tumor development/progression. ...

Role of STAT5 and epigenetics in lactation-associated upregulation of multidrug transporter ABCG2 in the mammary gland.

Am. J. Physiol. Endocrinol. Metab. 307(7) , E596-610, (2014)

The multidrug resistance efflux transporter ATP-binding cassette subfamily G member 2 (ABCG2) is not only overexpressed in certain drug-resistant cancers but is also highly expressed in the mammary gland during lactation, carrying xenobiotics and nutrients in...