4-methylcatechol
4-methylcatechol structure
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Common Name | 4-methylcatechol | ||
|---|---|---|---|---|
| CAS Number | 452-86-8 | Molecular Weight | 124.137 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 247.7±20.0 °C at 760 mmHg | |
| Molecular Formula | C7H8O2 | Melting Point | 67-69 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 121.1±16.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.
J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop ... |
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Verifying the botanical authenticity of commercial tannins through sugars and simple phenols profiles.
Food Chem. 206 , 274-83, (2016) Commercial tannins from several botanical sources and with different chemical and technological characteristics are used in the food and winemaking industries. Different ways to check their botanical authenticity have been studied in the last few years, throu... |
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Quantitative analysis of catechol and 4-methylcatechol in human urine.
Food Chem. Toxicol. 20(5) , 587-90, (1982) A method was developed for the quantitative analysis of catechol and 4-methylcatechol in human urine. [U-14C]Catechol was used as in internal standard. Urine was treated with beta-glucuronidase and sulphatase, acidified and extracted with ether. The ether ext... |
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Almond consumption reduces oxidative DNA damage and lipid peroxidation in male smokers.
J. Nutr. 137(12) , 2717-22, (2007) Smoking increases the risk of several chronic diseases associated with elevated oxidative stress status. Almonds are a good source of antioxidant nutrients and may diminish smoking-related biomarkers of oxidative stress. We investigated whether almond consump... |
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Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.
Rapid Commun. Mass Spectrom. 22(17) , 2629-38, (2008) Mercapturic acids are highly important and specific biomarkers of exposure to carcinogenic substances in occupational and environmental medicine. We have developed and validated a reliable, specific and very sensitive method for the simultaneous determination... |
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Measurement of urinary excretion of 5-hydroxymethyluracil in human by GC/NICI/MS: correlation with cigarette smoking, urinary TBARS and etheno DNA adduct.
Toxicol. Lett. 155(3) , 403-10, (2005) 5-Hydroxymethyluracil (5-HMU) is derived from radiation in addition to endogenous oxidative DNA damage and it is one of the most abundant DNA adducts. Human 5-HMU-DNA-glycosylase has been shown to repair this lesion. Whether urinary levels of 5-HMU is a valid... |
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Nicotine exposure can be detected in cerebrospinal fluid of active and passive smokers
J. Pharm. Biomed. Anal. 49(1) , 129-32, (2009) A simple, rapid and sensitive liquid chromatography/mass spectrometry (LC/MS) method has been utilized for the quantitative determination of nicotine and its major metabolite cotinine (COT) in human cerebrospinal fluid (CSF) of active and passive smokers. CSF... |
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A single-step extraction method for the determination of nicotine and cotinine in Jordanian smokers' blood and urine samples by RP-HPLC and GC-MS.
J. Chromatogr. Sci. 47(2) , 170-7, (2009) A simple, rapid, reliable, and low cost one-step extraction method is developed and validated for the determination of nicotine and cotinine in human plasma and urine in smokers using reversed-phase high-performance liquid chromatography (RP-HPLC) and gas chr... |
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Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles.
Clin. Chem. 48(9) , 1460-71, (2002) Assessment of nicotine metabolism and disposition has become an integral part of nicotine dependency treatment programs. Serum nicotine concentrations or urine cotinine concentrations can be used to guide nicotine patch dose to achieve biological concentratio... |
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Tetrahydrobiopterin restores endothelial function in long-term smokers.
J. Am. Coll. Cardiol. 35(1) , 71-5, (2000) We sought to test whether tetrahydrobiopterin (BH4) supplementation improves nitric oxide (NO) bioactivity in smokers.In smokers, endothelium-derived NO bioactivity is impaired. BH4 is an essential cofactor of NO synthase, and its deficiency decreases NO bioa... |