Luciferase, firefly
Luciferase, firefly structure
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Common Name | Luciferase, firefly | ||
|---|---|---|---|---|
| CAS Number | 61970-00-1 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H20N2O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 231.8 °F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.
Biochem. Biophys. Res. Commun. 465 , 232-8, (2015) A chemiluminescent method is proposed for quantitation of NO generation in cell cultures. The method is based on activation of soluble guanylyl cyclase by NO. The product of the guanylyl cyclase reaction, pyrophosphate, is converted to ATP by ATP sulfurylase ... |
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Cation-dependent folding of 3' cap-independent translation elements facilitates interaction of a 17-nucleotide conserved sequence with eIF4G.
Nucleic Acids Res. 41(5) , 3398-413, (2013) The 3'-untranslated regions of many plant viral RNAs contain cap-independent translation elements (CITEs) that drive translation initiation at the 5'-end of the mRNA. The barley yellow dwarf virus-like CITE (BTE) stimulates translation by binding the eIF4G su... |
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Vimentin is a component of a complex that binds to the 5'-UTR of human heme-regulated eIF2α kinase mRNA and regulates its translation.
FEBS Lett. 587(5) , 474-80, (2013) The human heme-regulated eIF2α kinase, also called the human heme-regulated inhibitor (hHRI) is significantly up-regulated particularly at the level of translation during stress. In this report we show that during lead-stress, the regulation of hHRI mRNA tran... |
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p16INK4a reporter mice reveal age-promoting effects of environmental toxicants.
J. Clin. Invest. 124(1) , 169-73, (2014) While murine-based systems to identify cancer-promoting agents (carcinogens) are established, models to identify compounds that promote aging (gerontogens) have not been described. For this purpose, we exploited the transcription of p16INK4a, which rises dyna... |
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Bioluminescent imaging of drug efflux at the blood-brain barrier mediated by the transporter ABCG2.
Proc. Natl. Acad. Sci. U. S. A. 110(51) , 20801-6, (2013) ATP-binding cassette (ABC) transporters are a group of transmembrane proteins that maintain chemical homeostasis through efflux of compounds out of organelles and cells. Among other functions, ABC transporters play a key role in protecting the brain parenchym... |
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Rational design and development of near-infrared-emitting firefly luciferins available in vivo.
Angew. Chem. Int. Ed. Engl. 52(4) , 1175-9, (2013)
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Efficient firefly chemi/bioluminescence: evidence for chemiexcitation resulting from the decomposition of a neutral firefly dioxetanone molecule.
J. Phys. Chem. A 117(1) , 94-100, (2013) Both experimental and theoretical methodologies were employed in order to study the possibility of excited state oxyluciferin being formed as the result of the decomposition of a neutral dioxetanone. Excitation measurements in water (at different pH values) a... |
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Angiopoietin-1 ameliorates inflammation-induced vascular leakage and improves functional impairment in a rat model of acute experimental autoimmune encephalomyelitis
Exp. Neurol. 261 , 245-57, (2014) Multiple sclerosis (MS) is characterized by perivascular inflammatory infiltration, secondary demyelination, and axonal loss in the central nervous system. Angiopoietin-1 (Ang-1) constitutes a family of endothelial growth factors that can inhibit MS-associate... |
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In vivo dynamics of estrogen receptor activity: the ERE-Luc model.
J. Steroid Biochem. Mol. Biol. 139 , 262-9, (2014) In recent years several studies demonstrated the presence of estrogen receptors in mammalian tissues and significantly improved our understanding of their ability to control biological processes in reproductive as well as non-reproductive organs. Considering ... |
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A guide to design and optimization of reporter assays for 3' untranslated region mediated regulation of mammalian messenger RNAs.
Methods 63(2) , 110-8, (2013) Post-transcriptional regulatory mechanisms are pervasive in the control of gene expression. Regulatory sequences within transcripts can control RNA processing, localization, translation efficiency, and stability of the RNA. Regulation is mediated by a diverse... |