demeton-S-methyl
demeton-S-methyl structure
|
Common Name | demeton-S-methyl | ||
|---|---|---|---|---|
| CAS Number | 919-86-8 | Molecular Weight | 230.28500 | |
| Density | 1.197g/cm3 | Boiling Point | 287.4ºC at 760 mmHg | |
| Molecular Formula | C6H15O3PS2 | Melting Point | <25℃ | |
| MSDS | USA | Flash Point | 2ºC | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
|
Mutagenesis of organophosphorus hydrolase to enhance hydrolysis of the nerve agent VX.
Biochem. Biophys. Res. Commun. 279(2) , 516-9, (2000) Organophosphorus hydrolase (OPH) is capable of hydrolyzing a wide variety of organophosphorus pesticides and chemical warfare agents. However, the hydrolytic activity of OPH against the warfare agent VX is less than 0.1% relative to its activity against parat... |
|
|
[First drafts of the Environmental Health Criteria (EHC) circulated for comments by IPCS in 1995-1996].
Eisei Shikenjo Hokoku. (114) , 95-8, (1996) Genes coding for cytochrome P450 are regulated by endogenous hormones such as the growth hormone, corticosteroids, thyroid, and sex hormones. Secretion of these hormones is regulated by the respective hypothalamus-pituitary-secretory organ axes. Since the bra... |
|
|
[The decrement-increment phenomenon in disorders of neuromuscular transmission by inhibition of acetylcholinesterase].
EEG EMG Z. Elektroenzephalogr. Elektromyogr. Verwandte Geb. 20(1) , 28-33, (1989) Repetitive stimulation of the median nerve elicited a so far unknown course of the muscle action potentials in four patients with organophosphate intoxications. The amplitude of the initial muscle action potential decreased with the second stimulus and gradua... |
|
|
[Chemico-toxicologic findings in fatal suicidal poisoning by demeton-S-methyl].
Z. Rechtsmed. 101(1) , 55-60, (1988) A case of lethal suicidal intoxication with demeton-S-methyl is reported. Capillary chromatography on wide-bore columns (CP-sil 5, 0.53 mm ID, 1 micron film thickness) was used for the quantitative determinations of this substance in the body fluids and tissu... |
|
|
Reductive cleavage of demeton-S-methyl by Corynebacterium glutamicum in cometabolism on more readily metabolizable substrates.
Appl. Environ. Microbiol. 66(3) , 1202-4, (2000) Corynebacterium glutamicum is able to biotransform demeton-S-methyl, an organophosphorus compound, during cometabolism with more readily metabolizable substrates. Among the cosubstrates used, fructose is the growth substrate that is most favorable for demeton... |
|
|
Degradation of nerve gases by CLECS and cells: kinetics of heterogenous systems.
Chem. Biol. Interact. 119-120 , 439-44, (1999) We have reported the enzymatic hydrolysis of phosphoro- and phosphonofluoridates and phosphoro- and phosphonothiolates and -thionates by an organophosphorus hydrolase (OPH) from Pseudomonas diminuta. In screening for other microbial sources of nerve gas hydro... |
|
|
[The repetitive muscular action potential in neuromuscular transmission disorders due to acetylcholinesterase inhibition].
EEG EMG Z. Elektroenzephalogr. Elektromyogr. Verwandte Geb. 19(2) , 85-91, (1988) Neuromuscular transmission was studied in 11 patients with organophosphate intoxication. The compound muscle action potential (MAP) was recorded from the thumb after single, repetitive (1-50 Hz) and paired stimulation. All patients showed a prolonged MAP. The... |
|
|
The kinetic study of the inhibition of human cholinesterases by demeton-S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate.
Toxicol. In Vitro 25(3) , 754-9, (2011) The organophosphorus insecticide, demeton-S-methyl (DSM), is considered as a good surrogate of the highly toxic nerve agent VX for skin absorption studies due to similar physico-chemical properties and in vitro percutaneous penetration profile. But, when skin... |
|
|
Organophosphate insecticide poisoning.
Anaesthesia 40(3) , 281-4, (1985) Organophosphate insecticides are widely used agents which are quickly absorbed through the skin and mucous membranes. The effects of acute exposure to these agents can be severe and intensive therapy may be required. Specific drugs are available to reverse th... |
|
|
Biochemical and histological effects of the aphicide demeton-S-methyl on house sparrows (Passer domesticus) under field conditions.
Bull. Environ. Contam. Toxicol. 48(3) , 360-6, (1992)
|