Comins' Reagent
Comins' Reagent structure
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Common Name | Comins' Reagent | ||
|---|---|---|---|---|
| CAS Number | 145100-51-2 | Molecular Weight | 392.683 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 358.3±52.0 °C at 760 mmHg | |
| Molecular Formula | C7H3ClF6N2O4S2 | Melting Point | 45-47 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 170.5±30.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Total synthesis of the antimitotic marine macrolide (-)-leiodermatolide.
Angew. Chem. Int. Ed. Engl. 53(10) , 2692-5, (2014) Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium sp. whose potentially novel tubulin-targeting mechanism of action makes it an exciting lead for anticancer drug discovery. In pursuit of a sustainable supply, we report ... |
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Tetrahedron Lett. 33 , 6299, (1992)
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Tetrahedron Lett. 44 , 9185, (2003)
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Synthesis 4 , 588, (2000)
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