vitexin
vitexin structure
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Common Name | vitexin | ||
|---|---|---|---|---|
| CAS Number | 3681-93-4 | Molecular Weight | 432.378 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 767.7±60.0 °C at 760 mmHg | |
| Molecular Formula | C21H20O10 | Melting Point | 256-257ºC | |
| MSDS | Chinese USA | Flash Point | 273.1±26.4 °C | |
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The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 968 , 105-11, (2014) SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therapeutic impo... |
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Activity-guided isolation, identification and quantification of biologically active isomeric compounds from folk medicinal plant Desmodium adscendens using high performance liquid chromatography with diode array detector, mass spectrometry and multidimentional nuclear magnetic resonance spectroscopy.
J. Pharm. Biomed. Anal. 102 , 54-63, (2014) The antioxidant activity of the crude extract (60% ethanol) from the leaves of Desmodium adscendens (Sw.) DC. (Fabaceae) was observed in DPPH, xanthine/xanthine oxidase, lipid peroxydation and neutrophils burst tests. Further activity-guided fractionation on ... |
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In vitro and in silico studies to explore structural features of flavonoids for aldehyde oxidase inhibition.
Arch. Pharm. (Weinheim) 347(10) , 738-47, (2014) Aldehyde oxidase (AO), an important enzyme in the biotransformation of drugs and xenobiotics, is inhibited by flavonoids. This enzyme can metabolize both aldehydes and N-heterocycles. In this work, a set of 15 flavonoids was assessed for inhibitory activity o... |
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Investigations of analyte-specific response saturation and dynamic range limitations in atmospheric pressure ionization mass spectrometry.
Anal. Chem. 86(21) , 10639-45, (2014) With this study, we investigated why some small molecules demonstrate narrow dynamic ranges in electrospray ionization-mass spectrometry (ESI-MS) and sought to establish conditions under which the dynamic range could be extended. Working curves were compared ... |
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Effects of vitexin on the pharmacokinetics and mRNA expression of CYP isozymes in rats.
Phytother Res. 29(3) , 366-72, (2015) In traditional therapy with Chinese medicine, vitexin has several pharmacological properties, including antinociceptive, antispasmodic, antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. Recently, vitexin was shown to protect the heart... |
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Orientin inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis.
Inflammation 37(5) , 1705-17, (2014) High mobility group box-1 (HMGB1) protein acts as a late mediator of severe vascular inflammatory conditions. Orientin has been known to have anxiolytic and antioxidative activities. However, the effect of orientin on HMGB1-induced inflammatory response has n... |
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Flavonoid analysis of buckwheat sprouts.
Food Chem. 170 , 97-101, (2014) It is known that common buckwheat sprouts contain several flavonoids, including orientin, isoorientin, vitexin, isovitexin, rutin, and quercetrin, whereas tartary buckwheat sprouts contain only rutin. In this study, we evaluated flavonoids present in buckwhea... |