Dicloxacillin sodium
Dicloxacillin sodium structure
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Common Name | Dicloxacillin sodium | ||
|---|---|---|---|---|
| CAS Number | 13412-64-1 | Molecular Weight | 510.323 | |
| Density | N/A | Boiling Point | 692.4ºC at 760mmHg | |
| Molecular Formula | C19H18Cl2N3NaO6S | Melting Point | 222-225°C | |
| MSDS | Chinese USA | Flash Point | 372.5ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o... |
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug Metab. Dispos. 38 , 2302-8, (2010) Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp... |
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Gingival pain: an unusual side effect of ziprasidone.
BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013) The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyr... |
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Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model.
Antimicrob. Agents Chemother. 53 , 1874-83, (2009) Antibiotic treatment of Staphylococcus aureus infections is often problematic due to the slow response to therapy and the high frequency of infection recurrence. The intracellular persistence of staphylococci has been recognized and could offer a good explana... |
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Do surface active parenteral formulations cause inflammation?
Int. J. Pharm. 484(1-2) , 246-51, (2015) Local irritation and inflammation at the site of administration are a common side effect following administration of parenteral formulations. Biological effects of surface (interfacial) activity in solutions are less well investigated than effects caused by o... |
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Spectrophotometric study of the reaction mechanism between DDQ as pi-acceptor and potassium iodate and flucloxacillin and dicloxacillin drugs and their determination in pure and in dosage forms.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 65(1) , 11-9, (2006) Two simple and accurate spectrophotometric methods are presented for the determination of beta-lactam drugs, flucloxacillin (Fluclox) and dicloxacillin (Diclox), in pure and in different pharmaceutical preparations. The charge transfer (CT) reactions between ... |
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The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen.
J. Neural Transm. Gen. Sect. 118(3) , 493-507, (2011) Increased brain α-synuclein (SNCA) protein expression resulting from gene duplication and triplication can cause a familial form of Parkinson's disease (PD). Dopaminergic neurons exhibit elevated iron levels that can accelerate toxic SNCA fibril formation. Ex... |
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Thioridazine potentiates the effect of a beta-lactam antibiotic against Staphylococcus aureus independently of mecA expression.
Res. Microbiol. 164(2) , 181-8, (2013) The neuroleptic antipsychotic derivate thioridazine has been shown to increase the susceptibility of a methicillin-resistant Staphylococcus aureus (MRSA) isolate towards dicloxacillin. The aim of this study was to investigate the combinatorial effect of the t... |
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Development of a validated HPLC method for the determination of four penicillin antibiotics in pharmaceuticals and human biological fluids.
J. Sep. Sci. 29(11) , 1550-60, (2006) A quantitative method for the determination of four penicillin antibiotics, amoxicillin (AMO), oxacillin (OXA), cloxacillin (CLO), and dicloxacillin (DICLO), has been developed. Separation was achieved on an Inertsil ODS-3 (250 x 4 mm, 5 microm) column after ... |
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Pyomyositis in children: early diagnosis and treatment.
J. Pediatr. Surg. 44(11) , 2173-8, (2009) This study was conducted to evaluate early diagnosis, clinical course, and treatment outcome in children with pyomyositis.Between 2001 and 2006, 6 children with a mean age of 7.2 years were diagnosed and treated for pyomyositis in our clinic. The most common ... |