Subtilisin (Compound proteinase)

Subtilisin (Compound proteinase) Structure
Subtilisin (Compound proteinase) structure
Common Name Subtilisin (Compound proteinase)
CAS Number 9014-01-1 Molecular Weight 238.19786
Density 1.3 Boiling Point N/A
Molecular Formula C11H9N3O2.Na Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Danger

Abnormalities in Expression of Structural, Barrier and Differentiation Related Proteins, and Chondroitin Sulfate in Feline and Human Interstitial Cystitis.

J. Urol. 194 , 571-7, (2015)

We analyzed the urothelium of cats diagnosed with feline interstitial cystitis to determine whether abnormalities in protein expression patterns could be detected and whether the expression pattern was similar to that in patients with human interstitial cysti...

Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease.

Autophagy 11(2) , 385-402, (2015)

Mitochondria-induced oxidative stress and flawed autophagy are common features of neurodegenerative and lysosomal storage diseases (LSDs). Although defective autophagy is particularly prominent in Pompe disease, mitochondrial function has escaped examination ...

Cardioprotective effects of early and late aerobic exercise training in experimental pulmonary arterial hypertension.

Basic Res. Cardiol. 110 , 57, (2015)

Clinical studies suggest that aerobic exercise can exert beneficial effects in pulmonary arterial hypertension (PAH), but the underlying mechanisms are largely unknown. We compared the impact of early or late aerobic exercise training on right ventricular fun...

Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18.

Sci. Rep. 5 , 11863, (2015)

Serpins generally serve as inhibitors that utilize a mobile reactive center loop (RCL) as bait to trap protease targets. Here, we present the crystal structure of serpin18 from Bombyx mori at 1.65 Å resolution, which has a very short and stable RCL. Activity ...

Cytogenetic significance of chromosome 17 aberrations and P53 gene mutations as prognostic markers in oral squamous cell carcinoma.

Diagn. Pathol. 10 , 2, (2015)

Cytogenetic analysis has detected an accumulation of genetic lesions in oral cancers. Numerical changes in chromosome 17 might be associated with an up-regulation of p53 gene, and could contribute to critical events in carcinogenesis. The aim of this study wa...

Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function.

Gene 514(2) , 99-104, (2013)

A 255-bp cDNA encoding an 84-amino acid residue (aa) precursor protein containing 8 half-cysteines was cloned from the skin of the frog, Ceratophrys calcarata. By sequence comparison and signal peptide prediction, the precursor was predicted to release a 63-a...

Effects of the KIF2C neck peptide on microtubules: lateral disintegration of microtubules and β-structure formation.

FEBS J. 280(7) , 1681-92, (2013)

Members of the kinesin-13 sub-family, including KIF2C, depolymerize microtubules. The positive charge-rich 'neck' region extending from the N-terminus of the catalytic head is considered to be important in the depolymerization activity. Chemically synthesized...

Coupling of epithelial Na+ and Cl- channels by direct and indirect activation by serine proteases.

Am. J. Physiol. Cell Physiol. 303(9) , C936-46, (2012)

The mammalian collecting duct (CD) is continuously exposed to urinary proteases. The CD expresses an epithelial Na(+) channel (ENaC) that is activated after cleavage by serine proteases. ENaC also exists at the plasma membrane in the uncleaved form, rendering...

In silico characterization of alkaline proteases from different species of Aspergillus.

Appl. Biochem. Biotechnol. 166(1) , 243-57, (2012)

A total of 49 protein sequences of alkaline proteases retrieved from GenBank representing different species of Aspergillus have been characterized for various physiochemical properties, homology search, multiple sequence alignment, motif, and super family sea...

Purification, characterization and identification of a senescence related serine protease in dark-induced senescent wheat leaves.

Phytochemistry 95 , 118-26, (2013)

Senescence-related proteases play important roles in leaf senescence by regulating protein degradation and nutrient recycling. A 98.9kDa senescence-related protease EP3 in wheat leaves was purified by ammonium sulfate precipitation, Q-Sepharose fast flow anio...