Curdlan
Curdlan structure
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Common Name | Curdlan | ||
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| CAS Number | 54724-00-4 | Molecular Weight | 504.437 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 902.8±65.0 °C at 760 mmHg | |
| Molecular Formula | (C6H10O5)n | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 499.8±34.3 °C | |
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Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury.
J. Neuroinflammation 12 , 109, (2015) Large-scale macrophage infiltration and reactive astrogliosis are hallmarks of early spinal cord injury (SCI) pathology. The exact nature of the macrophage response and relationship between these phenomena have not been explored in detail. Here, we have inves... |
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Green synthesis of silver nanoparticles using 4-acetamido-TEMPO-oxidized curdlan.
Carbohydr. Polym. 97(2) , 391-7, (2013) A facile, simple, and eco-friendly method using 4-acetamido-2,2,6,6-tetramethypiperidine-1-oxyl radical-oxidized curdlan (Oc) as both reducing and stabilizing agents was developed for the fabrication of silver nanoparticles (AgNPs) from silver nitrate (AgNO₃)... |
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Structural characteristics and antioxidant activities of different families of 4-acetamido-TEMPO-oxidised curdlan.
Food Chem. 143 , 530-5, (2014) Regioselective oxidation was applied to commercial curdlan for the preparation of its water-soluble derivatives with improved antioxidant activities, using a 4-acetamido-2,2, 6,6-tetramethylpiperidine-1-oxyl radical/NaClO/NaClO2 system at pH 4.8 and 40°C. The... |
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Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition.
J. Thorac. Cardiovasc. Surg. 284 , 28263-75, (2009) The long pentraxin 3 (PTX3) is a multifunctional soluble pattern recognition molecule that is crucial in innate immune protection against opportunistic fungal pathogens such as Aspergillus fumigatus. The mechanisms that mediate downstream effects of PTX3 are ... |
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Down-regulation of tumor necrosis factor-alpha, moderate reduction of interleukin-1beta, but not interleukin-6 or interleukin-10, by glucan immunomodulators curdlan sulfate and lentinan.
Int. J. Immunopharmacol. 19 , 463-468, (1997) The effects of glucan-based immunomodulators curdlan sulfate (CRDS) and lentinan on cytokine production stimulated by lipopolysaccharide (LPS) in bacillus Calmette-Guerin (BCG)-primed mice were investigated. Pretreatment with CRDS or lentinan before LPS admin... |
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Functions of Manduca sexta hemolymph proteinases HP6 and HP8 in two innate immune pathways.
J. Thorac. Cardiovasc. Surg. 284 , 19716-26, (2009) Serine proteinases in insect plasma have been implicated in two types of immune responses; that is, activation of prophenoloxidase (proPO) and activation of cytokine-like proteins. We have identified more than 20 serine proteinases in hemolymph of the tobacco... |
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An insect multiligand recognition protein functions as an opsonin for the phagocytosis of microorganisms.
J. Thorac. Cardiovasc. Surg. 285 , 25243-50, (2010) We characterize a novel pathogen recognition protein obtained from the lepidopteran Galleria mellonella. This protein recognizes Escherichia coli, Micrococcus luteus, and Candida albicans via specific binding to lipopolysaccharides, lipoteichoic acid, and bet... |
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Curdlan, a (1----3)-beta-D-glucan from Alcaligenes faecalis var. myxogenes IFO13140, activates the alternative complement pathway by heat treatment.
Immunol. Lett. 26 , 95-97, (1990) From the results of consumption experiments of guinea pig complement, Curdlan, a (1----3)-beta-D-glucan obtained from Alcaligenes faecalis var. myxogenes IFO13140, has been found to lack the ability to activate complement when unheated or preheated at either ... |
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Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.
Arthritis Rheumatology 66(7) , 1755-67, (2014) Spondyloarthritides (SpA) occur in 1% of the population and include ankylosing spondylitis (AS) and arthropathy of inflammatory bowel disease (IBD), with characteristic spondylitis, arthritis, enthesitis, and IBD. Genetic studies implicate interleukin-23 (IL-... |
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Differential control of Mincle-dependent cord factor recognition and macrophage responses by the transcription factors C/EBPβ and HIF1α.
J. Immunol. 193(7) , 3664-75, (2014) Trehalose-6,6-dimycolate (TDM), the mycobacterial cord factor, and its synthetic analog Trehalose-6,6-dibehenate (TDB) bind to the C-type lectin receptors macrophage-inducible C-type lectin (Mincle) and Mcl to activate macrophages. Genetically, the transcript... |