Chymopapain

Chymopapain Structure
Chymopapain structure
Common Name Chymopapain
CAS Number 9001-09-6 Molecular Weight 328.84576
Density N/A Boiling Point N/A
Molecular Formula H5M*2NOP2YI.CH4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Purification and characterization of extracellular cysteine protease inhibitor, ECPI-2, from Chlorella sp.

J. Biosci. Bioeng. 101(2) , 166-71, (2006)

An extracellular cysteine protease inhibitor (ECPI-2) was purified to homogeneity from the culture filtrate of Chlorella sp. 4533 by the combination of various column chromatographies. The molecular mass of the inhibitor was estimated to be 340 kDa by SDS-PAG...

Surface Plasmon Resonance Imaging biosensor for cystatin determination based on the application of bromelain, ficin and chymopapain.

Folia Histochem. Cytobiol. 50(1) , 130-6, (2012)

A Surface Plasmon Resonance Imaging (SPRI) sensor based on bromelain or chymopapain or ficin has been developed for specific cystatin determination. Cystatin was captured from a solution by immobilized bromelain or chymopapain or ficin due to the formation of...

Papaya latex enzymes capable of detoxification of gliadin.

Amino Acids 38(1) , 155-65, (2010)

Assay of fractions obtained from ion exchange chromatography of papaya latex on CM Sephadex-C50, size exclusion chromatography on Sephacryl S-300 and size exclusion HPLC have provided an insight into the relative contributions of the gluten-detoxifying enzyme...

Intradiscal therapies for discogenic pain.

Semin. Musculoskelet. Radiol. 10(2) , 125-35, (2006)

Since the first injection of chymopapain in 1963, percutaneous intradiscal therapies have been used to treat discogenic back and leg pain. The percutaneous discectomy techniques treat contained disc herniations not by resecting the prolapsed disc material but...

Study of blood metabolism and urinary excretion of chymopapain following intradiscal injection using a high-sensitivity enzyme immunoassay.

J. Orthop. Sci. 10(2) , 206-13, (2005)

To develop chymopapain-induced chemonucleolysis as an established treatment, it is necessary to determine the kinetics of chymopapain in blood and urine following intradiscal injection. To investigate the rate of blood metabolism and urinary excretion of chym...

Surgical interventions for lumbar disc prolapse: updated Cochrane Review.

Spine 32(16) , 1735-47, (2007)

An updated Cochrane Review.To assess the effects of surgical interventions for the treatment of lumbar disc prolapse.Disc prolapse accounts for 5% of low back disorders yet is one of the most common reasons for surgery. There is still little scientific eviden...

Applicability of the chymopapain gene used as endogenous reference gene for transgenic huanong no. 1 papaya detection.

J. Agric. Food Chem. 57(15) , 6502-9, (2009)

The virus-resistant papaya (Carica papaya L.), Huanong no. 1, was the genetically modified (GM) fruit approved for growing in China in 2006. To implement the labeling regulation of GM papaya and its derivates, the development of papaya endogenous reference ge...

Dual colour, microarray-based, analysis of 10,000 protease substrates.

Chem. Commun. (Camb.) (38) , 3984-6, (2006)

A 10,000 member PNA-encoded library of FRET based peptides was synthesised for global analysis of protease cleavage specificity; analysis was achieved using a DNA microarray and consumed minimal quantities of enzyme (60 pmole) and library (3.5 nmole).

Transforaminal posterolateral endoscopic discectomy with or without the combination of a low-dose chymopapain: a prospective randomized study in 280 consecutive cases.

Spine 31(24) , E890-7, (2006)

A prospective randomized study involving 280 consecutive cases of lumbar disc herniation managed either by an endoscopic discectomy alone or an endoscopic discectomy combined with an intradiscal injection of a low dose (1000 U) of chymopapain.To compare outco...

Structural characterization of the papaya cysteine proteinases at low pH.

Biochem. Biophys. Res. Commun. 341(2) , 620-6, (2006)

Current control of gastrointestinal nematodes relies primarily on the use of synthetic drugs and encounters serious problems of resistance. Oral administration of plant cysteine proteinases, known to be capable of damaging nematode cuticles, has recently been...