Moloney Murine Leukemia Virus enzyme
Moloney Murine Leukemia Virus enzyme structure
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Common Name | Moloney Murine Leukemia Virus enzyme | ||
|---|---|---|---|---|
| CAS Number | 9068-38-6 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.
Genes Dev. 28(7) , 723-34, (2014) The multifunctional CCCTC-binding factor (CTCF) protein exhibits a broad range of functions, including that of insulator and higher-order chromatin organizer. We found that CTCF comprises a previously unrecognized region that is necessary and sufficient to bi... |
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Mitochondrial dysfunction and nuclear-mitochondrial shuttling of TERT are involved in cell proliferation arrest induced by G-quadruplex ligands
FEBS Lett. 587(11) , 1656-62, (2013) • DODC is more efficient in cell growth inhibition than TMPyP4. • Both DODC and TMPyP4 cause nuclear-mitochondrial shuttling of TERT. • Perturbation of mitochondrial function may account for the toxicity of DODC. |
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miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo
Exp. Cell Res. 319(10) , 1575-85, (2013) Decrease in expression of the tumor suppressor microRNA-138 (miR-138) correlates well with an increase in telomerase activity in many human cancers. The ability of almost all human cancer cells to grow indefinitely is dependent on presence of telomerase activ... |
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RNA recognition by the DNA end-binding Ku heterodimer.
RNA 19(6) , 841-51, (2013) Most nucleic acid-binding proteins selectively bind either DNA or RNA, but not both nucleic acids. The Saccharomyces cerevisiae Ku heterodimer is unusual in that it has two very different biologically relevant binding modes: (1) Ku is a sequence-nonspecific d... |
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Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma.
Blood 123(12) , 1850-9, (2014) Telomere erosion may be counteracted by telomerase. Here we explored telomere length (TL) and telomerase activity (TA) in primary cutaneous T-cell lymphoma (CTCL) by using quantitative polymerase chain reaction and interphase quantitative fluorescence in situ... |
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[Ovarian aging and infertility].
Ginekol. Pol. 84(4) , 298-304, (2013) The biological state of the ovum remains the key element in normal reproduction. Age-related decrease in the number of oocytes, as well as disturbed neuroendocrine function of the ovary and lesions in the uterus, contribute to reduced fertility. Decreasing nu... |
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High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization.
Am. J. Physiol. Lung Cell. Mol. Physiol. 306(7) , L661-71, (2014) Angiogenic expansion of the vasa vasorum (VV) is an important contributor to pulmonary vascular remodeling in the pathogenesis of pulmonary hypertension (PH). High proliferative potential endothelial progenitor-like cells have been described in vascular remod... |
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PinX1, a novel target gene of p53, is suppressed by HPV16 E6 in cervical cancer cells.
Biochim. Biophys. Acta 1839(2) , 88-96, (2014) The aberrant activation of telomerase is critical for the initiation and development of human cervical cancer, which is dependent on the activation of human telomerase reverse transcriptase (hTERT). Recently, Pin2/TRF1-interacting protein X1 (PinX1) has been ... |
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Evaluation of urinary human telomerase reverse transcriptase mRNA and scatter factor protein as urine markers for diagnosis of bladder cancer.
Clin. Lab. 59(3-4) , 317-23, (2013) Expression of the human telomerase reverse transcriptase (hTERT) gene, which codes for the catalytic subunit of telomerase is considered an important tumor marker used for bladder cancer detection being found in the majority of cancer cells. Scatter Factor (S... |
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Telomere length and telomerase reverse transcriptase mRNA expression in patients with hepatitis C.
Hepatogastroenterology. 60(127) , 1713-6, (2013) Shortened telomeres reflect genetic instability that might lead to increased aneuploidy and malignant transformations. Chronic hepatitis C (HCV) viral infection is considered a pre-neoplastic condition that might progress to hepatocellular carcinoma. We evalu... |