γ-Linolenoyl-CoA
γ-Linolenoyl-CoA structure
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Common Name | γ-Linolenoyl-CoA | ||
|---|---|---|---|---|
| CAS Number | 18172-33-3 | Molecular Weight | 1027.948 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 598.6ºC at 760mmHg | |
| Molecular Formula | C20H20N2O3 | Melting Point | 245-246ºC | |
| MSDS | Chinese USA | Flash Point | 315.8ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium.
Arthritis. Res. Ther. 16(3) , R121, (2014) Acid-sensing ion channel 3 (ASIC3) is expressed in synoviocytes, activated by decreases in pH, and reduces inflammation in animal models of inflammatory arthritis. The purpose of the current study was to characterize potential mechanisms underlying the contro... |
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Store-operated calcium entry compensates fast ER calcium loss in resting hippocampal neurons.
Cell Calcium 58 , 147-59, (2015) The endoplasmic reticulum (ER) acts as a dynamic calcium store and is involved in the generation of specific patterns of calcium signals in neurons. Calcium is mobilized from the ER store by multiple signaling cascades, and neuronal activity is known to regul... |
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Mechanisms of the sarcoplasmic reticulum Ca2+ release induced by P2X receptor activation in mesenteric artery myocytes.
Pharmacol. Rep. 66(3) , 363-72, (2014) ATP is one of the principal sympathetic neurotransmitters which contracts vascular smooth muscle cells (SMCs) via activation of ionotropic P2X receptors (P2XRs). We have recently demonstrated that contraction of the guinea pig small mesenteric arteries evoked... |
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Selective facilitation of LTP in the ventral hippocampus by calcium stores.
Hippocampus 22(7) , 1635-44, (2012) The effects of low concentrations of caffeine and ryanodine on field excitatory postsynaptic potentials (EPSPs) and long-term potentiation (LTP) were studied in CA1 region of slices of dorsal and ventral hippocampus (DH and VH, respectively). There was a stri... |
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Activation of muscarinic acetylcholine receptors elevates intracellular Ca(2+) concentrations in accessory lobe neurons of the chick.
J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. 201(4) , 385-94, (2015) Accessory lobes are protrusions located at the lateral sides of the spinal cord of chicks and it has been proposed that they play a role as a sensory organ for equilibrium during walking. We have reported that functional neurons exist in the accessory lobe. A... |
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Pulsed infrared radiation excites cultured neonatal spiral and vestibular ganglion neurons by modulating mitochondrial calcium cycling.
J. Neurophysiol. 112(6) , 1246-55, (2014) Cochlear implants are currently the most effective solution for profound sensorineural hearing loss, and vestibular prostheses are under development to treat bilateral vestibulopathies. Electrical current spread in these neuroprostheses limits channel indepen... |
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Menthol inhibits detrusor contractility independently of TRPM8 activation.
PLoS ONE 9(11) , e111616, (2014) Agonists such as icilin and menthol can activate the cool temperature-sensitive ion channel TRPM8. However, biological responses to menthol may occur independently of TRPM8 activation. In the rodent urinary bladder, menthol facilitates the micturition reflex ... |
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Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis.
J. Physiol. 592(Pt 16) , 3443-61, (2014) Store-operated calcium channels (SOCs) are calcium-selective cation channels that mediate calcium entry in many different cell types. Store-operated calcium entry (SOCE) is involved in various cellular functions. Increasing evidence suggests that impairment o... |
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Astrocyte Ca2+ Signaling Drives Inversion of Neurovascular Coupling after Subarachnoid Hemorrhage.
J. Neurosci. 35 , 13375-84, (2015) Physiologically, neurovascular coupling (NVC) matches focal increases in neuronal activity with local arteriolar dilation. Astrocytes participate in NVC by sensing increased neurotransmission and releasing vasoactive agents (e.g., K(+)) from perivascular endf... |
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Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.
J. Neurosci. 35 , 15837-46, (2015) The endoplasmic reticulum (ER) plays crucial roles in intracellular Ca(2+) signaling, serving as both a source and sink of Ca(2+), and regulating a variety of physiological and pathophysiological events in neurons in the brain. However, spatiotemporal Ca(2+) ... |