ethane-1,2-diaminium dichloride

ethane-1,2-diaminium dichloride Structure
ethane-1,2-diaminium dichloride structure
Common Name ethane-1,2-diaminium dichloride
CAS Number 333-18-6 Molecular Weight 133.020
Density 1.159g/cm3 Boiling Point 472.9ºC at 760mmHg
Molecular Formula C2H10Cl2N2 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 239.8ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Synthesis and X-ray structures of novel macrocycles and macrobicycles containing N,N-di(pyrrolylmethyl)-N-methylamine moiety: preliminary anion binding study.

Inorg. Chem. 51(16) , 9029-38, (2012)

The [2 + 2] Schiff base condensation reactions between the newly synthesized dialdehyde, N,N-di(α-formylpyrrolyl-α-methyl)-N-methylamine), and ethylenediamine or p-phenylenediamine dihydrochloride readily afforded the 30- and 34-membered large size macrocycle...

Surface-modified P(HEMA-co-MAA) nanogel carriers for oral vaccine delivery: design, characterization, and in vitro targeting evaluation.

Biomacromolecules 15(7) , 2725-34, (2014)

Oral drug delivery is a route of choice for vaccine administration because of its noninvasive nature and thus efforts have focused on efficient delivery of vaccine antigens to mucosal sites. An effective oral vaccine delivery system must protect the antigen f...

Acute cadmium administration to rats exerts both immunosuppressive and proinflammatory effects in spleen.

Toxicology 326 , 96-108, (2014)

Conflicting data (both suppression and augmentation as well as lack of the effect) exist in respect to cadmium (Cd) and splenic T cell-based immune cell activity. Spleen is also the site of innate immune responses but impact of Cd on this type of immunity has...

Toxicity of oral cadmium intake: Impact on gut immunity.

Toxicol. Lett. 237 , 89-99, (2015)

Gastrointestinal tract is one of the main targets of cadmium (Cd), an important food and drinking water contaminant. In the present study, the effect of subchronic (30 days) oral (in water) intake of 5ppm and 50ppm of cadmium on immune responses in the gut wa...

Effect of Green Tea Extract Encapsulated Into Chitosan Nanoparticles on Hepatic Fibrosis Collagen Fibers Assessed by Atomic Force Microscopy in Rat Hepatic Fibrosis Model.

J. Nanosci. Nanotechnol. 15 , 6452-9, (2015)

The present study examined the effect of Green Tea Extract (GTE) encapsulated into Chitosan Nanoparticles (CS-NPs) on hepatic fibrosis in rat model as determined by atomic force microscopy (AFM). The bioactive compounds in GTE encapsulated into CS-NPs were de...

Remediation of Cu(II), Ni(II), and Cr(III) ions from simulated wastewater by dendrimer/titania composites.

J. Environ. Manage. 117 , 50-7, (2013)

Generation 4 polyamidoamine (PAMAM) dendrimers with ethylenediamine cores (G4-OH) were immobilized on titania (TiO(2)) and examined as novel metal chelation materials. Characterization results indicate both the effective immobilization of dendrimers onto tita...

Synthesis of ethylenediamine modified chitosan and evaluation for removal of divalent metal ions.

Carbohydr. Polym. 97(2) , 530-6, (2013)

Selective modification of chitosan has been achieved by incorporating ethylene-1,2-diamine molecule in a regioselective manner using N-phthaloylchitosan and chloro-6-deoxy N-phthaloylchitosan as precursors. The present modification results in additional nitro...

New hyaluronic acid based brush copolymers synthesized by atom transfer radical polymerization.

Carbohydr. Polym. 92(2) , 1054-63, (2013)

In this work, an efficient method for the synthesis of hyaluronic acid based brush copolymers using atom transfer radical polymerization (ATRP) has been reported. At first, two different hyaluronic acid (HA) based macroinitiators have been prepared and then t...

Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing versus top-down.

J. Am. Soc. Mass Spectrom. 24(3) , 410-20, (2013)

We report identification of the binding sites for an organometallic ruthenium anticancer complex [(η (6)-biphenyl)Ru(en)Cl][PF6] (1; en = ethylenediamine) on the 15-mer single-stranded oligodeoxynucleotides (ODNs), 5'-CTCTCTX7G8Y9CTTCTC-3' [X = Y = T (I); X =...

The role of the helper lipid dioleoylphosphatidylethanolamine (DOPE) for DNA transfection cooperating with a cationic lipid bearing ethylenediamine.

Biochim. Biophys. Acta 1828(2) , 412-8, (2013)

Gene therapy is expected to treat various incurable diseases including viral infections, autoimmune disorders, and cancers. Cationic lipids (CL) have been used as carriers of therapeutic DNAs for gene therapy because they can form a complex with DNA and such ...