(Bromomethyl)cyclopropane
(Bromomethyl)cyclopropane structure
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Common Name | (Bromomethyl)cyclopropane | ||
|---|---|---|---|---|
| CAS Number | 7051-34-5 | Molecular Weight | 135.00 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 106.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H7Br | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 41.7±0.0 °C | |
| Symbol |
GHS02 |
Signal Word | Warning | |
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Iron-catalyzed cross-coupling of alkyl halides with alkenyl grignard reagents.
Angew. Chem. Int. Ed. Engl. 46 , 6521, (2007)
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Simple iron-amine catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing beta-hydrogens.
Chem. Commun. (Camb.) (33) , 4161-3, (2005) Mixtures of iron(III) chloride and appropriate amine ligands are active catalysts for the coupling of aryl Grignard reagents with primary and secondary alkyl halide substrates bearing beta-hydrogens, under mild and simple reaction conditions. |
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Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
J. Med. Chem. 47 , 1400, (2004) A series of pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone (7a-k) were synthesized and evaluated for binding affinity at the opioid delta, micro, and kappa receptors in brain membranes using radioligand binding assays and for functiona... |
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Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core.
Bioorg. Med. Chem. Lett. 14 , 377, (2004) A novel series of piperazines appended to a succinamide backbone were synthesized and found to have a high affinity for the melanocortin-4 receptor (IC(50)s ranging from <0.1 to 200 nM). Both agonists and antagonists of MC4R were prepared by modifying the gro... |
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(S)-N-[1-(4-cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons.
Bioorg. Med. Chem. Lett. 14 , 1991, (2004) (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide ((S)-2) was identified as a potent and efficacious KCNQ2 opener. This compound demonstrated significant activity in reducing neuronal hyperexcitability i... |