o-Tolylacetic acid
o-Tolylacetic acid structure
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Common Name | o-Tolylacetic acid | ||
|---|---|---|---|---|
| CAS Number | 644-36-0 | Molecular Weight | 150.174 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 279.3±9.0 °C at 760 mmHg | |
| Molecular Formula | C9H10O2 | Melting Point | 88-90 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 176.5±13.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.
J. Neurosci. 35(14) , 5664-79, (2015) The Ca(2+) channelopathies caused by mutations of the CACNA1A gene that encodes the pore-forming subunit of the human Cav2.1 (P/Q-type) voltage-gated Ca(2+) channel include episodic ataxia type 2 (EA2). Although, in EA2 the emphasis has been on cerebellar dys... |
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Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome.
J. Neurosci. 35(9) , 3938-45, (2015) The Fmr1 knock-out mouse model of fragile X syndrome (Fmr1(-/y)) has an epileptogenic phenotype that is triggered by group I metabotropic glutamate receptor (mGluR) activation. We found that a membrane-permeable peptide that disrupts mGluR5 interactions with ... |
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Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.
J. Neurosci. 35 , 15837-46, (2015) The endoplasmic reticulum (ER) plays crucial roles in intracellular Ca(2+) signaling, serving as both a source and sink of Ca(2+), and regulating a variety of physiological and pathophysiological events in neurons in the brain. However, spatiotemporal Ca(2+) ... |