NH2-C4-NH-Boc

NH2-C4-NH-Boc Structure
NH2-C4-NH-Boc structure
Common Name NH2-C4-NH-Boc
CAS Number 68076-36-8 Molecular Weight 188.267
Density 1.0±0.1 g/cm3 Boiling Point 292.9±23.0 °C at 760 mmHg
Molecular Formula C9H20N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 130.9±22.6 °C
Symbol GHS05
GHS05
Signal Word Danger

Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P₁ positions by peptoid monomers.

Biopolymers 104 , 206-12, (2015)

Recently, we described a process of trypsin-assisted peptide splicing of analogs of trypsin inhibitor SFTI-1, that seems to be very similar to proteasome-catalyzed peptide splicing. Here, we show, for the first time, that a peptide-peptoid hybrid (peptomer) c...

Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogues.

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In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for tubulin binding affinity, in vitro cytotoxicity against cultured mouse B-16 cells, and ability to pr...

Synthesis and biological evaluation of new citrate-based siderophores as potential probes for the mechanism of iron uptake in mycobacteria.

J. Med. Chem. 45 , 2056, (2002)

Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferriox...

18F-labeled insulin: a prosthetic group methodology for incorporation of a positron emitter into peptides and proteins.

Biochemistry 28 , 4801, (1989)

In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl pr...

Rationally designed peptoids modulate aggregation of amyloid-beta 40.

ACS Chem. Neurosci. 5(7) , 552-8, (2014)

Alzheimer's disease (AD) is the most common form of dementia and the sixth leading cause of death in the United States. Plaques composed of aggregated amyloid-beta protein (Aβ) accumulate between the neural cells in the brain and are associated with dementia ...

Synthesis of Amphiphilic Block Copolypept(o)ides by Bifunctional Initiators: Making PeptoMicelles Redox Sensitive.

Macromol. Rapid Commun. 36 , 2083-91, (2016)

In this work, the synthesis of polypeptoid-block-polypeptide copolymers (block copolypept(o)ides) based on bifunctional initiators is described, which introduces a distinct chemical entity at the connection between both blocks. With a view towards redox-sensi...

H.H. Wassermann et al

Tetrahedron 58 , 7177, (2002)

M. McWatt, G.J. Boons, R. Kuroda

European J. Org. Chem. , 2535, (2001)