Triethylsilane

Triethylsilane Structure
Triethylsilane structure
Common Name Triethylsilane
CAS Number 617-86-7 Molecular Weight 116.277
Density 0.728 g/mL at 25 °C(lit.) Boiling Point 107.5±0.0 °C at 760 mmHg
Molecular Formula C6H16Si Melting Point -157°C
MSDS Chinese USA Flash Point -3.9±0.0 °C
Symbol GHS02
GHS02
Signal Word Danger

Colloidal nanocrystals of lithiated group 14 elements.

Angew. Chem. Int. Ed. Engl. 53(52) , 14527-32, (2014)

The synthesis of colloidal nanocrystals (NCs) of lithiated group 14 elements (Z=Si, Ge, and Sn) is reported, which are Li4.4 Si, Li3.75 Si, Li4.4 Ge, and Li4.4 Sn. Lix Z compounds are highly reactive and cannot be synthesized by existing methods. The success ...

Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain

Bioorg. Med. Chem. Lett. 21 , 3676-3681, (2011)

Starting from the oxindole 2a identified through a high-throughput screening campaign, a series of Na(V)1.7 blockers were developed. Following the elimination of undesirable structural features, preliminary optimization of the oxindole C-3 and N-1 substituent...

Stereochemical control in the reduction of 2-chromanols.

Org. Lett. 8 , 4711, (2006)

[reaction: see text] Reduction of C5-substituted 2-hydroxychromans selectively provides 2,4-cis-chromans using large silane reductants and 2,4-trans-chromans using the smaller silane PhSiH(3). The stereochemical outcome has been rationalized on the basis of a...

Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome.

J. Med. Chem. 56(2) , 568-83, (2013)

Stearoyl-CoA desaturase-1 (SCD1) catalyzes de novo synthesis of monounsaturated fatty acids from saturated fatty acids. Studies have demonstrated that rodents lacking a functional SCD1 gene have an improved metabolic profile, including reduced weight gain, lo...

Multi-modal detection of colon malignancy by NIR-tagged recognition polymers and ultrasound contrast agents.

Int. J. Pharm. 478(2) , 504-16, (2015)

To increase colonoscopy capability to discriminate benign from malignant polyps, we suggest combining two imaging approaches based on targeted polymeric platforms. Water-soluble cationized polyacrylamide (CPAA) was tagged with the near infrared (NIR) dye IR-7...

Nonradioactive, ultrasensitive site-specific protein-protein photocrosslinking: interactions of alpha-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2.

Nucleic Acids Res. 36(19) , 6143-54, (2008)

We have developed an approach that enables nonradioactive, ultrasensitive (attamole sensitivity) site-specific protein-protein photocrosslinking, and we have applied the approach to the analysis of interactions of alpha-helix 2 (H2) of human TATA-element bind...