Chlorophenol Red

Chlorophenol Red Structure
Chlorophenol Red structure
Common Name Chlorophenol Red
CAS Number 4430-20-0 Molecular Weight 423.26700
Density 1.605g/cm3 Boiling Point 583ºC at 760mmHg
Molecular Formula C19H12Cl2O5S Melting Point 261 °C
MSDS Chinese USA Flash Point 306.4ºC

Trypanocidal Activity of Long Chain Diamines and Aminoalcohols.

Molecules 20 , 11554-68, (2015)

Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0-6.6 times) than the reference compound nifurtimox. From them, three aminoal...

Immune response profile elicited by the model antigen ovalbumin expressed in fusion with the bacterial OprI lipoprotein.

Mol. Immunol. 64(1) , 36-45, (2015)

The use of immunogenic formulations targeting pattern recognition receptors towards modulation of immune responses is a promising strategy to develop better vaccines against infectious and malignant diseases. Molecules targeting TLR2 offer interesting propert...

Enhancement of MHC-I antigen presentation via architectural control of pH-responsive, endosomolytic polymer nanoparticles.

AAPS J. 17(2) , 358-69, (2015)

Protein-based vaccines offer a number of important advantages over organism-based vaccines but generally elicit poor CD8(+) T cell responses. We have previously demonstrated that pH-responsive, endosomolytic polymers can enhance protein antigen delivery to ma...

Detection of marine microalgal biotoxins using bioassays based on functional expression of tunicate xenobiotic receptors in yeast.

Toxicon 95 , 13-22, (2015)

Marine microalgae can produce biotoxins that cause widespread poisoning in marine ecosystems and may also affect human health. While established microalgal biotoxins are detectable using chemical methods, a need remains for robust, inexpensive bioassays. Liga...

Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture.

Toxicol. Sci. 140(2) , 283-97, (2014)

Polychlorinated biphenyls (PCBs) are persistent environmental toxicants, present in 100% of U.S. adults and dose-dependently associated with obesity and non-alcoholic fatty liver disease (NAFLD). PCBs are predicted to interact with receptors previously implic...

Azithromycin is able to control Toxoplasma gondii infection in human villous explants.

J. Transl. Med. 12 , 132, (2014)

Although Toxoplasma gondii infection is normally asymptomatic, severe cases of toxoplasmosis may occur in immunosuppressed patients or congenitally infected newborns. When a fetal infection is established, the recommended treatment is a combination of pyrimet...

Octaarginine-modified liposomes enhance cross-presentation by promoting the C-terminal trimming of antigen peptide.

Mol. Pharm. 11(8) , 2787-95, (2014)

Exogenous antigen proteolysis by proteasomes and amino peptidases is essential for the production of mature major histocompatibility complex class I (MHC-I) peptides to induce cross-presentation. We report here that when liposomes are modified with octaargini...

Potential novel antibiotics from HTS targeting the virulence-regulating transcription factor, VirF, from Shigella flexneri.

J. Antibiot. 67(5) , 379-86, (2014)

VirF is an AraC-type transcriptional regulator responsible for activating the transcription of virulence genes required for the intracellular invasion and cell-to-cell spread of Shigella flexneri. Gene disruption studies have validated VirF as a potential tar...

Dipeptides catalyze rapid peptide exchange on MHC class I molecules.

Proc. Natl. Acad. Sci. U. S. A. 112(1) , 202-7, (2015)

Peptide ligand selection by MHC class I molecules, which occurs by iterative optimization, is the centerpiece of immunodominance in antiviral and antitumor immune responses. For its understanding, the molecular mechanisms of peptide binding and dissociation b...