3-Hydroxyisovaleric acid
3-Hydroxyisovaleric acid structure
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Common Name | 3-Hydroxyisovaleric acid | ||
|---|---|---|---|---|
| CAS Number | 625-08-1 | Molecular Weight | 118.13100 | |
| Density | 0.938 g/mL at 25 °C(lit.) | Boiling Point | 88 °C1 mm Hg(lit.) | |
| Molecular Formula | C5H10O3 | Melting Point | −80 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 113 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
J. Nutr. 144(12) , 1977-84, (2014) Biotin functions as a cofactor for several carboxylase enzymes with key roles in metabolism. At present, the dietary requirement for biotin is unknown and intake recommendations are provided as Adequate Intakes (AIs). The biotin AI for adults and pregnant wom... |
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HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Si... |
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Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.
Clin. Chem. 40(6) , 862-6, (1994) Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days to 16 years, subdivided into five age groups. We quantifie... |
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Prediction of skeletal muscle and fat mass in patients with advanced cancer using a metabolomic approach.
J. Nutr. 142(1) , 14-21, (2012) Urine and plasma metabolites originate from endogenous metabolic pathways in different organs and exogenous sources (diet). Urine and plasma were obtained from advanced cancer patients and investigated to determine if variations in lean and fat mass, dietary ... |
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Quantitative analysis for organic acids in biological samples: batch isolation followed by gas chromatographic-mass spectrometric analysis.
Clin. Chem. 35(4) , 587-95, (1989) This new method for qualitative and quantitative determination of organic acids, aldehydes, and ketones in biological samples is effective for use with urine, plasma, and amniotic fluid, and it requires no deproteinization. Isolation by batch-wise liquid part... |
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The human cerebrospinal fluid metabolome
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 871(2) , 164-73, (2008) With continuing improvements in analytical technology and an increased interest in comprehensive metabolic profiling of biofluids and tissues, there is a growing need to develop comprehensive reference resources for certain clinically important biofluids, suc... |
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SPE-NMR metabolite sub-profiling of urine.
Anal. Bioanal. Chem 404(8) , 2349-61, (2012) NMR-based metabolite profiling of urine is a fast and reproducible method for detection of numerous metabolites with diverse chemical properties. However, signal overlap in the (1)H NMR profiles of human urine may hamper quantification and identification of m... |
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Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.
Kidney Int. 79(11) , 1244-53, (2011) Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used multidimensional-multinuclear nuclear magnetic resonance (... |
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Organic acids in the second morning urine in a healthy Swiss paediatric population.
Clin. Chem. Lab Med. 41(12) , 1642-58, (2003) Organic acid analysis is used for the early detection/ exclusion and for the follow-up of inherited disorders of amino acid and organic acid metabolism. Urinary organic acid concentrations in 417 healthy Caucasian children (1 day to 17 years of age) were dete... |
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Effect of HMB/Arg/Gln on the prevention of radiation dermatitis in head and neck cancer patients treated with concurrent chemoradiotherapy.
Jpn. J. Clin. Oncol. 44(5) , 422-7, (2014) This prospective randomized Phase II study was designed to evaluate the preventive effect of an oral nutrition supplement composed of beta-hydroxy-beta-methylbutyrate, arginine and glutamine (beta-hydroxy-beta-methylbutyrate/arginine/glutamine) on radiation d... |