(-)-Citrinin

(-)-Citrinin Structure
(-)-Citrinin structure
Common Name (-)-Citrinin
CAS Number 518-75-2 Molecular Weight 250.247
Density 1.4±0.1 g/cm3 Boiling Point 409.8±45.0 °C at 760 mmHg
Molecular Formula C13H14O5 Melting Point 175°C (dec.)
MSDS Chinese USA Flash Point 156.6±22.2 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Corncob hydrolysate, an efficient substrate for Monascus pigment production through submerged fermentation.

Biotechnol. Appl. Biochem. 61(6) , 716-23, (2014)

Monascus pigment has traditionally been produced by the fermentation of Monascus using rice powder or glucose as a culture substrate. Submerged fermentation can produce stable Monascus pigment yield and control the accumulation of the by-product, citrinin, wh...

Chemical profiling and quantification of monacolins and citrinin in red yeast rice commercial raw materials and dietary supplements using liquid chromatography-accurate QToF mass spectrometry: Chemometrics application.

J. Pharm. Biomed. Anal. 100 , 243-53, (2014)

Red yeast rice (RYR) is prepared by fermenting rice with various strains of the yeast Monascus spp of the Aspergillaceae family. Depending on the Monascus strains and the fermentation conditions, the products may contain monacolins, pigments and citrinin as s...

Characterization of Anti-Citrinin Specific ScFvs Selected from Non-Immunized Mouse Splenocytes by Eukaryotic Ribosome Display.

PLoS ONE 10 , e0131482, (2015)

Single chain variable fragments (scFvs) against citrinin (CIT) were selected from a scFv library constructed from the splenocytes of non-immunized mice by an improved eukaryotic ribosome display technology in this study. Bovine serum albumin (BSA)/ CIT-BSA an...

Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin.

Int. J. Food Microbiol. 192 , 1-6, (2015)

Penicillium verrucosum is a fungus that can produce ochratoxin A and citrinin, two structurally related nephrotoxic mycotoxins. P. verrucosum usually occurs on wheat but can occasionally also be found in NaCl rich habitats such as salted cheeses or olives, in...

Toxicity of the mycotoxin citrinin and its metabolite dihydrocitrinone and of mixtures of citrinin and ochratoxin A in vitro.

Arch. Toxicol. 88(5) , 1097-107, (2014)

Citrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by several species of the genera Aspergillus, Penicillium and Monascus. Both can be present as contaminants in various food commodities and in animal feed. The occurrence and toxicity of OTA and hu...

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter—Organic anion transporter1 (Oat1)

Bioorg. Med. Chem. 19 , 3320-40, (2011)

Organic anion transporter 1 (Oat1), first identified as NKT, is a multispecific transporter responsible for the handling of drugs and toxins in the kidney and choroid plexus, but its normal physiological role appears to be in small molecule metabolite regulat...

A structure-switchable aptasensor for aflatoxin B1 detection based on assembly of an aptamer/split DNAzyme.

Anal. Chim. Acta 886 , 182-7, (2015)

An ultrasensitive, colorimetric and homogeneous strategy for aflatoxin B1 (AFB1) detection, which uses a DNA aptamer and two split DNAzyme halves, has been developed. Split halves of a hemin-binding DNAzymes is combined with an AFB1 aptamer to generate a homo...

Citrinin dimers from the halotolerant fungus Penicillium citrinum B-57.

J. Nat. Prod. 71 , 543-6, (2008)

In order to search for structurally novel and bioactive natural compounds from microorganisms, a halotolerant fungal strain, Penicillium citrinum B-57, which mainly produces citrinin derivatives, was isolated from sediments collected from the Jilantai salt fi...

Identification of a high-affinity monoclonal antibody against ochratoxin A and its application in enzyme-linked immunosorbent assay.

Toxicon 106 , 89-96, (2015)

Ochratoxin A (OTA) is one of the most commonly occurring mycotoxins produced by some species of Aspergillus and can contaminate cereal and cereal products. A high-affinity anti-OTA monoclonal antibody (mAb) was generated from a hybridoma cell line 2D8 using s...

Preparation of an immunoaffinity column for the clean-up of fermented food samples contaminated with citrinin.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 30(2) , 389-94, (2013)

An immunoaffinity column (IAC) for the clean-up of citrinin-contaminated food samples was prepared by using silica gel immobilised with a anti-citrinin antibody. Antibodies produced against citrinin-bovine serum albumin (BSA) were covalently immobilised onto a...