Misoprostol acid

Misoprostol acid Structure
Misoprostol acid structure
Common Name Misoprostol acid
CAS Number 112137-89-0 Molecular Weight 368.508
Density 1.1±0.1 g/cm3 Boiling Point 538.3±50.0 °C at 760 mmHg
Molecular Formula C21H36O5 Melting Point N/A
MSDS Chinese USA Flash Point 293.4±26.6 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Active management of the third stage of labour: prevention and treatment of postpartum hemorrhage.

J. Obstet. Gynaecol. Can. 31 , 980-993, (2009)

To review the clinical aspects of postpartum hemorrhage (PPH) and provide guidelines to assist clinicians in the prevention and management of PPH. These guidelines are an update from the previous Society of Obstetricians and Gynaecologists of Canada (SOGC) cl...

Management of NSAID-induced gastrointestinal toxicity: focus on proton pump inhibitors.

Drugs 69 , 51-69, (2009)

The association between NSAIDs and the presence of upper gastrointestinal (GI) complications is well established. Evidence that acid aggravates NSAID-induced injury provides a rationale for minimizing such damage by acid suppression. Proton pump inhibitors (P...

Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial.

Lancet 2 , 1277, (1988)

A double-blind, placebo-controlled study was carried out to see whether the synthetic E prostaglandin, misoprostol, would prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs). 420 patients with osteoarthritis and NSAID-associated ab...

The use of misoprostol in obstetrics and gynaecology.

BJOG 116 , 61-69, (2009)

Misoprostol, although originally introduced as a therapy for gastric ulcers, is now widely used in reproductive health. For some indications it is now the optimal choice, whilst for others it provides an important alternative, especially in low-resource setti...

Misoprostol for the prevention and treatment of postpartum hemorrhage.

Expert Opin. Investig. Drugs 21 , 235-250, (2012)

Uterotonic drugs are recommended for the prevention and treatment of postpartum hemorrhage (PPH), and oxytocin is considered the gold standard for both indications due to its established efficacy and safety. Unfortunately, access to oxytocin is still limited ...