112137-89-0
112137-89-0 structure
- Name: Misoprostol acid
- Chemical Name: (+/-)-15-deoxy-[16rs]-16-hydroxy-16-methylprostaglandin e1
- CAS Number: 112137-89-0
- Molecular Formula: C21H36O5
- Molecular Weight: 368.508
- Catalog: API Hormone and endocrine-regulating drugs Prostaglandins
- Create Date: 2016-05-02 07:42:49
- Modify Date: 2024-01-09 20:27:51
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Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].
| Name | (+/-)-15-deoxy-[16rs]-16-hydroxy-16-methylprostaglandin e1 |
|---|---|
| Synonyms |
Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, (11α,13E)-
(11α,13E)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid Misoprostol Acid MISOPROSTOL FREE ACID |
| Description | Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2]. |
|---|---|
| Related Catalog | |
| Target |
Prostaglandin E1 (PGE1)[1] |
| In Vivo | Unlike the Misoprostol, Misoprostol acid is detectable in plasma. Misoprostol is a lipophilic methyl ester prodrug and is readily metabolized to the free acid, which is the biologically active form. Misoprostol is used worldwide for a variety of indications in obstetrics and gynecology. Misoprostol has both gastric antisecretory and mucosal protective effects[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 538.3±50.0 °C at 760 mmHg |
| Molecular Formula | C21H36O5 |
| Molecular Weight | 368.508 |
| Flash Point | 293.4±26.6 °C |
| Exact Mass | 368.256287 |
| PSA | 94.83000 |
| LogP | 2.45 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.543 |
| Storage condition | −20°C |
| Symbol |
GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H315-H319-H335-H361 |
| Precautionary Statements | P261-P281-P301 + P310-P305 + P351 + P338 |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R45 |
| Safety Phrases | 53-22-36/37/39-45 |
| RIDADR | UN 2810 6 |
| WGK Germany | 2 |