3-Acetylpyridine
3-Acetylpyridine structure
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Common Name | 3-Acetylpyridine | ||
|---|---|---|---|---|
| CAS Number | 350-03-8 | Molecular Weight | 121.137 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 220.8±13.0 °C at 760 mmHg | |
| Molecular Formula | C7H7NO | Melting Point | 11-13 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 150.0±0.0 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Ionic matrices pre-spotted matrix-assisted laser desorption/ionization plates for patient maker following in course of treatment, drug titration, and MALDI mass spectrometry imaging.
Anal. Biochem. 434(1) , 187-98, (2013) In the current study, we compared plastic matrix-assisted laser desorption/ionization (MALDI) plates pre-spotted with different solid ionic matrices. Data reflect that after 3 months of storage, the standards were oxidized in α-cyano-4-hydroxycinnamic acid (H... |
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Cyanoacetic acid hydrazones of 3-(and 4-)acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents.
Arch. Pharm. (Weinheim) 339(1) , 14-23, (2006) Two new acetylpyridinehydrazones derived from cyanoacetic acid hydrazide have been synthesized namely: cyanoacetic acid (1-pyridin-3 or 4-yl-ethylidene) hydrazides (1a,b). and some derived ring systems: 2-imino or 2-oxo-2H-chromenes (2a,b and 3a,b), substitut... |
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Definitive endoderm differentiation of human-induced pluripotent stem cells using signaling molecules and IDE1 in three-dimensional polymer scaffold.
J. Biomed. Mater. Res. A 102(11) , 4027-36, (2014) Human-induced pluripotent stem cells (hiPSCs) are considered to be potentially able to differentiate into all human cell lineages and thus hold promise as an unlimited source for cell replacement therapies in clinical applications. Definitive endoderm (DE) fo... |
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Attenuation of activity-induced increases in cerebellar blood flow by lesion of the inferior olive.
Am. J. Physiol. Heart Circ. Physiol. 285(3) , H1177-82, (2003) We sought to define the contribution of the climbing fibers (CF), one of the major inputs to Purkinje neurons, to the increase in cerebellar blood flow (BFcrb) produced by activation of the cerebellar cortex. The neurotoxin 3-acetylpyridine was used to lesion... |
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In vivo 4-aminopyridine treatment alters the neurotoxin 3-acetylpyridine-induced plastic changes in intrinsic electrophysiological properties of rat cerebellar Purkinje neurones.
Eur. J. Pharmacol. 642(1-3) , 56-65, (2010) Electrophysiological dysfunction of Purkinje cells causes cerebellar ataxia. Recent studies indicated that 4-aminopyridine (4-AP) can prevent the attacks in patients with episodic ataxia type 2. However, the cellular mechanism(s) by which 4-AP might be benefi... |
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[Effect of nicotinamide adenine dinucleotide on the serotoninergic mediator system in the rat brain during 3-acetylpyridine administration].
Vopr. Med. Khim. 48(3) , 264-70, (2002) The effect of administration of 3-acetylpyridine (antivitamin B3), on rat brain serotoninergic and NAD receptor systems was investigated. The injection of 3-acetylpyridine to rats caused a decrease of NAD and serotonin content in the brain and changes in [U-1... |
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Episodic vestibular disruption following ablation of the inferior olive in rats: behavioral correlates.
Behav. Brain Res. 175(1) , 128-38, (2006) The experiments herein investigate whether the behavioral responses to transient and episodic vestibular disruption and permanent ablation are distinct in the absence of climbing fiber input. Subjects in group 1 received an IP injection of PBS followed by an ... |
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3-acetylpyridine reduces tongue protrusion force but does not abolish lick rhythm in the rat.
Brain Res. 920(1-2) , 1-9, (2001) Data from other laboratories suggest that neurons in the inferior olivary nucleus (IO) may play a role in the modulation of rhythmic tongue movements in rats. Because of its known harmful effects on neurons of the IO, it was suspected that administration of t... |
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Purification and characterization of rat liver enzyme catalyzing stereoselective reduction of acetylpyridines.
Chirality 17(8) , 494-500, (2005) Acetylpyridines (1-3) are known as aroma components of foods, perfumes, and smoking suppressants, showing several biological activities and constituting part of the structure of some important biologically active compounds. We purified and characterized an en... |
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Olivocerebellar projections are necessary for exogenous trophic factors to delay heredo-Purkinje cell degeneration.
Brain Res. 986(1-2) , 54-62, (2003) The temporally protracted heredodegeneration of cerebellar Purkinje cells in shaker mutant rats can be modified: ablation of the inferior olive accelerates their degeneration whereas chronic intraventricular infusion of trophic factors extends their survival.... |