Cyanogen bromide
Cyanogen bromide structure
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Common Name | Cyanogen bromide | ||
|---|---|---|---|---|
| CAS Number | 506-68-3 | Molecular Weight | 105.921 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | 61.5±9.0 °C at 760 mmHg | |
| Molecular Formula | CBrN | Melting Point | 50-53 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | -9.0±18.7 °C | |
| Symbol |
GHS05, GHS06, GHS09 |
Signal Word | Danger | |
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Breast and prostate cancer patients differ significantly in their serum Thymidine kinase 1 (TK1) specific activities compared with those hematological malignancies and blood donors: implications of using serum TK1 as a biomarker.
BMC Cancer 15 , 66, (2015) Thymidine kinase 1 (TK1) is a cellular enzyme involved in DNA precursor synthesis, and its activity has been used as a proliferation marker for monitoring malignant diseases. Here, for the first time, we evaluated both TK1 activity and protein levels in sera ... |
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AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.
J. Pathol. 235(4) , 581-92, (2015) Biomechanical strain imposed by age-related thickening of the basal lamina and augmented tissue stiffness in the prostate gland coincides with increased cancer risk. Here we hypothesized that the structural alterations in the basal lamina associated with age ... |
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Fingerprinting desmosine-containing elastin peptides.
J. Am. Soc. Mass Spectrom. 26(5) , 762-73, (2015) Elastin is a vital protein of the extracellular matrix of jawed vertebrates and provides elasticity to numerous tissues. It is secreted in the form of its soluble precursor tropoelastin, which is subsequently cross-linked in the course of the elastic fiber as... |
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The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function.
Biochem. J. 467(3) , 473-86, (2015) Acid ecto-phosphatase activity has been implicated in Leishmania donovani promastigote virulence. In the present study, we report data contributing to the molecular/structural and functional characterization of the L. donovani LdMAcP (L. donovani membrane aci... |
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Interaction of ceruloplasmin with eosinophil peroxidase as compared to its interplay with myeloperoxidase: Reciprocal effect on enzymatic properties.
Free Radic. Res. 49 , 800-11, (2015) Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are involved in the development of halogenative stress during inflammation. We previously described a complex between MPO and ceruloplasmin (CP). Considering the high structural homology between MPO and EP... |
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Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor.
Cell Death Dis. 5 , e1409, (2014) Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong surviv... |
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Site-specific glycosylation of secretory immunoglobulin A from human colostrum.
J. Proteome Res. 14(3) , 1335-49, (2015) Secretory immunoglobulin A (sIgA) is a major glycoprotein in milk and plays a key role in mediating immune protection of the gut mucosa. Although it is a highly glycosylated protein, its site-specific glycosylation and associated glycan micro-heterogeneity ha... |
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"Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation.
J. Allergy Clin. Immunol. 134(6) , 1394-1401.e4, (2014) Naturally occurring IgE-specific IgG autoantibodies have been identified in patients with asthma and other diseases, but their spectrum of functions is poorly understood.Address the hypothesis that: (i) IgG anti-IgE autoantibodies are detectable in the serum ... |
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Hypothiocyanous acid oxidation of tubulin cysteines inhibits microtubule polymerization.
Arch. Biochem. Biophys. 541 , 67-73, (2014) Thiol oxidation is a probable outcome of cellular oxidative stress and is linked to degenerative disease progression. In addition, protein thiol redox reactions are increasingly identified as a mechanism to regulate protein structure and function. We assessed... |
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New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
Mol. Pharmacol. 86(3) , 342-57, (2014) Small-conductance (KCa2) and intermediate-conductance (KCa3.1) calcium-activated K(+) channels are voltage-independent and share a common calcium/calmodulin-mediated gating mechanism. Existing positive gating modulators like EBIO, NS309, or SKA-31 activate bo... |