Hoechst 33342
Hoechst 33342 structure
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Common Name | Hoechst 33342 | ||
|---|---|---|---|---|
| CAS Number | 23491-52-3 | Molecular Weight | 452.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28N6O | Melting Point | 268ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Comparative in vitro study on magnetic iron oxide nanoparticles for MRI tracking of adipose tissue-derived progenitor cells.
PLoS ONE 9(9) , e108055, (2014) Magnetic resonance imaging (MRI) using measurement of the transverse relaxation time (R2*) is to be considered as a promising approach for cell tracking experiments to evaluate the fate of transplanted progenitor cells and develop successful cell therapies fo... |
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DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.
J. Exp. Med. 211(13) , 2549-66, (2014) DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when DOCK8-deficient T and NK cells migrate through confined spaces, they develop cell shape and nuclear defo... |
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Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.
J. Biol. Chem. 290 , 16723-43, (2015) Human protein arginine methyltransferase (PRMT) 9 symmetrically dimethylates arginine residues on splicing factor SF3B2 (SAP145) and has been functionally linked to the regulation of alternative splicing of pre-mRNA. Site-directed mutagenesis studies on this ... |
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HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.
Br. J. Pharmacol. 172 , 3028-42, (2015) Angiotensin II (AngII) and IL-1β are involved in cardiovascular diseases through the induction of inflammatory pathways. HuR is an adenylate- and uridylate-rich element (ARE)-binding protein involved in the mRNA stabilization of many genes. This study investi... |
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Compound K-induced apoptosis of human hepatocellular carcinoma MHCC97-H cells in vitro.
Oncol. Rep. 32(1) , 325-31, (2014) An intestinal bacterial metabolite of ginseng protopanaxadiol saponin, 20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol (compound K), has been reported to induce apoptosis in a variety of cancer cells. However, the precise mechanisms induced by compound K in h... |
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Spatial distribution of 5-hydroxymethyl cytosine in rat brain and temporal distribution in striatum.
Neurochem. Res. 40(4) , 688-97, (2015) Recently, 5-hydroxymethyl cytosine (5hmC) was identified in higher organisms as a novel epigenetic modification factor, and was found to be substantially enriched in the central nervous system relative to many other tissues and cell types. Additionally, epige... |
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Dual fluorescent labelling of the human malaria parasite Plasmodium falciparum for the analysis of the ABC type transporter pfmdr2.
Malaria Journal 11 , 371, (2012) The study of the Plasmodium falciparum heavy metal transporter gene pfmdr2 employed radioactive labelled heavy metal. As the use of radioactive isotopes shrank considerably during the last few years, resulting in the cessation of the production of some isotop... |
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Nova1 is a master regulator of alternative splicing in pancreatic beta cells.
Nucleic Acids Res. 42(18) , 11818-30, (2014) Alternative splicing (AS) is a fundamental mechanism for the regulation of gene expression. It affects more than 90% of human genes but its role in the regulation of pancreatic beta cells, the producers of insulin, remains unknown. Our recently published data... |
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Epirubicin-adsorbed nanodiamonds kill chemoresistant hepatic cancer stem cells.
ACS Nano 8(12) , 12151-66, (2014) Chemoresistance is a primary cause of treatment failure in cancer and a common property of tumor-initiating cancer stem cells. Overcoming mechanisms of chemoresistance, particularly in cancer stem cells, can markedly enhance cancer therapy and prevent recurre... |
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A dimerized HMX1 inhibits EPHA6/epha4b in mouse and zebrafish retinas.
PLoS ONE 9(6) , e100096, (2014) HMX1 is a homeobox-containing transcription factor implicated in eye development and responsible for the oculo-auricular syndrome of Schorderet-Munier-Franceschetti. HMX1 is composed of two exons with three conserved domains in exon 2, a homeobox and two doma... |