Pivaloyl chloride

Pivaloyl chloride Structure
Pivaloyl chloride structure
Common Name Pivaloyl chloride
CAS Number 3282-30-2 Molecular Weight 120.577
Density 1.0±0.1 g/cm3 Boiling Point 107.2±8.0 °C at 760 mmHg
Molecular Formula C5H9ClO Melting Point -56 °C
MSDS Chinese USA Flash Point 8.9±0.0 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger

Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3.

Bioorg. Med. Chem. 23(5) , 1123-34, (2015)

Proteinase 3 (Pr3), and human neutrophil elastase (HNE) are two major neutrophilic serine proteases (NsPs) expressed in neutrophil azurophil granules. Emerging data suggest that excessive release of proteases mediates tissue damage, and therefore prolonged ne...

Selective pivaloylation of 2-acetamido-2-deoxy sugars.

Carbohydr. Res. 182(2) , 197-205, (1988)

Selective pivaloylation of 2-acetamido-2-deoxy-D-glucose, its methyl alpha- and beta-glycosides, and the methyl alpha-glycoside of N-acetyl-D-muramic acid under various conditions has been studied. The structures of the products were established by 1H-n.m.r. ...

Selective pivaloylation and diphenylacetylation of cyclomalto-oligosaccharides.

Carbohydr. Res. 262(2) , 271-82, (1994)

Regioselective acylation of cyclomalto-oligosaccharides was achieved using pivaloyl and diphenylacetyl chlorides. The reaction of cyclomaltohexaose (1) with pivaloyl chloride gave the hexakis(2,6-di-O-pivaloyl) derivative 19 in 66% yield. Similar reaction wit...

Tetrahedron 49 , 599, (1993)

Angew. Chem. Int. Ed. Engl. 32 , 72, (1993)

Tetrahedron Lett. 35 , 2369, (1994)

J. Org. Chem. 59 , 1703, (1994)

J. Carbohydr. Chem. 12 , 841, (1993)

Synthesis and utilization of saccharide intermediates.

Carbohydr. Res. 248 , 129, (1993)

A new method has been developed for preparation of partially pivaloylated saccharides in one step from readily available starting materials. These intermediates were used in the synthesis of disaccharides and a glucosteroid.

4'-pivaloyl substituted thymidine as a precursor for the thymyl radical: an EPR spectroscopic study.

ChemPhysChem 5(2) , 270-4, (2004)