Loxoprofen
Loxoprofen structure
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Common Name | Loxoprofen | ||
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| CAS Number | 68767-14-6 | Molecular Weight | 246.302 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 417.9±20.0 °C at 760 mmHg | |
| Molecular Formula | C15H18O3 | Melting Point | 108.5 - 111ºC | |
| MSDS | Chinese USA | Flash Point | 220.7±18.3 °C | |
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Determination of nonsteroidal anti-inflammatory drugs in human tear and plasma samples using ultra-fast liquid chromatography-tandem mass spectrometry.
Jpn. J. Ophthalmol. 59 , 364-71, (2015) To evaluate a new rapid and sensitive method for analyzing human tears and plasma for nonsteroidal anti-inflammatory drugs (NSAIDs) and investigate the influence of the transfer of NSAIDs in an ocular lesion.In this cross-over study, a single dose of 200 mg o... |
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Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, low-dose aspirin, and antihypertensive drugs: a case-control study.
J. Gastroenterol. Hepatol. 30(2) , 292-8, (2015) The associations between antithrombotic or antihypertensive drugs and peptic ulcer bleeding (PUB) remain unknown, particularly in Asia, where Helicobacter pylori infection is prevalent. This study aims to evaluate the risks of PUB from antithrombotic drugs, a... |
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Effect of X-ray exposure on the pharmaceutical quality of drug tablets using X-ray inspection equipment.
Drug Dev. Ind. Pharm. 41 , 953-8, (2015) X-ray inspection equipment is widely used to detect missing materials and defective goods in opaque containers. Its application has been expanded to the pharmaceutical industry to detect the presence of drug tablets in aluminum foil press-through packaging. H... |
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Influence of nonsteroidal anti-inflammatory drugs on the antiplatelet effects of aspirin in rats.
Biol. Pharm. Bull. 34(2) , 233-7, (2011) Low-dose aspirin acts by irreversibly acetylating internal cyclooxygenase-1 (COX-1) on platelets, thereby suppressing platelet aggregation. Because nonsteroidal anti-inflammatory drugs (NSAIDs) also inhibit COX-1, the antiplatelet effects of aspirin may be su... |
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Protective effect of geranylgeranylacetone against loxoprofen sodium-induced small intestinal lesions in rats.
Eur. J. Pharmacol. 652(1-3) , 121-5, (2011) Nonsteroidal anti-inflammatory drugs induce small intestinal ulcers but the preventive measures against it remain unknown. So we evaluated the effect of geranylgeranylacetone (GGA), a mucosal protectant, on both the mucus content and loxoprofen sodium-induced... |
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Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat.
Biol. Pharm. Bull. 35(12) , 2230-7, (2012) Non-steroidal anti-inflammatory drugs (NSAIDs) comprise one of the most frequently used classes of medicines in the world; however, NSAIDs have significant side effects, such as gastroenteropathy, and rheumatoid arthritis patients taking NSAIDs are more susce... |
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Unilateral eyelid angioedema with congestion of the right bulbar conjunctiva due to loxoprofen sodium.
Cutis. 87(1) , 41-3, (2011) Angioedema is a variant of urticaria that causes deep dermal and subcutaneous swelling. It frequently is a unilateral reaction and usually lasts for several hours but may persist for several days. We report 2 cases of angioedema that involved the right upper ... |
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Heart failure assocated with pregabalin.
Pain Physician 15(4) , E536-7, (2012)
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Cutaneous polyarteritis nodosa induced by Mycobacterium tuberculosis.
J. Dermatol. 39(8) , 738-9, (2012)
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New therapeutic strategy for amino acid medicine: prophylactic and healing promoting effect of monosodium glutamate against NSAID-induced enteropathy.
J. Pharmacol. Sci. 118(2) , 131-7, (2012) We reviewed the effect of monosodium glutamate (MSG) on the development and healing of nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal lesions in rats. Loxoprofen (60 mg/kg, p.o.) induced lesions in the small intestine within 24 h, accomp... |