- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Loxoprofen
- Price: ￥88.0/5g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Loxoprofen Sodium
- Price: $200.0/100mg $400.0/250mg $800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Loxoprofen
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Loxoprofen API
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
68767-14-6
68767-14-6 structure
- Name: Loxoprofen
- Chemical Name: loxoprofen
- CAS Number: 68767-14-6
- Molecular Formula: C15H18O3
- Molecular Weight: 246.302
- Catalog: API Antipyretic analgesics Non-steroidal anti-inflammatory drugs
- Create Date: 2018-04-20 08:00:00
- Modify Date: 2024-01-02 18:41:31
-
Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.
| Name | loxoprofen |
|---|---|
| Synonyms |
IOXOPROFEN
MFCD00864331 KOLOXO Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]- 2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid Loxoprofen |
| Description | Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. |
|---|---|
| Related Catalog | |
| Target |
COX-1:6.5 μM (IC50, in human whole blood) COX-2:13.5 μM (IC50, in human whole blood) |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 417.9±20.0 °C at 760 mmHg |
| Melting Point | 108.5 - 111ºC |
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.302 |
| Flash Point | 220.7±18.3 °C |
| Exact Mass | 246.125595 |
| PSA | 54.37000 |
| LogP | 1.87 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.568 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918300090 |
|
~%
68767-14-6 |
| Literature: US4161538 A1, ; |
|
~%
68767-14-6 |
| Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372 |
|
~%
68767-14-6 |
| Literature: Synthetic Communications, , vol. 14, # 14 p. 1365 - 1372 |
|
~84%
68767-14-6 |
| Literature: Hurusawa, Shinya; Nakamura, Shuji; Yagi, Sayoko; Kurihara, Takushi; Hamada, Yasumasa; Shioiri, Takayuki Synthetic Communications, 1984 , vol. 14, # 14 p. 1365 - 1372 |
|
~%
68767-14-6 |
| Literature: Journal of Medicinal Chemistry, , vol. 27, # 2 p. 212 - 216 |
| Precursor 4 | |
|---|---|
| DownStream 1 | |
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |