Desogestrel
Desogestrel structure
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Common Name | Desogestrel | ||
|---|---|---|---|---|
| CAS Number | 54024-22-5 | Molecular Weight | 310.473 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 428.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C22H30O | Melting Point | 109-110ºC | |
| MSDS | Chinese USA | Flash Point | 187.9±21.7 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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Changes in the size of rectovaginal endometriotic nodules infiltrating the rectum during hormonal therapies.
Arch. Gynecol. Obstet. 287(3) , 447-53, (2013) To evaluate the changes in the volume of rectovaginal endometriotic nodules infiltrating the rectum during 12-month treatment with hormonal therapies.This prospective, non-randomized, self-controlled clinical trial included patients with rectovaginal endometr... |
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The risk of venous thrombosis in women over 50 years old using oral contraception or postmenopausal hormone therapy.
J. Thromb. Haemost. 11(1) , 124-31, (2013) Oral contraception (OC) and postmenopausal hormone therapy (HT) can be used to alleviate menopausal symptoms. However, the risk of venous thrombosis (VT) associated with OC use in women over 50 years old has never been assessed and the two preparations have n... |
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Progestogen-only contraceptive pill compared with combined oral contraceptive in the treatment of pain symptoms caused by endometriosis in patients with migraine without aura.
Eur. J. Obstet. Gynecol. Reprod. Biol. 179 , 63-8, (2014) Evaluate patient satisfaction at 6-month treatment in women with symptomatic rectovaginal endometriosis and migraine without aura with (progestogen-only contraceptive pill, POP versus sequential combined oral contraceptives, COC) STUDY DESIGN: A patient prefe... |
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Progestins in preventive hormone therapy. Including pharmacology of the new progestins, desogestrel, norgestimate, and gestodene: are there advantages?
Obstet. Gynecol. Clin. North Am. 21(2) , 299-319, (1994) Clofarabine was the latest new drug to be approved, in 2004, for relapsed or refractory acute lymphoblastic leukaemia (ALL). To investigate its value in the frontline treatment of ALL we applied clofarabine 5 × 40 mg/m(2) in combination with pegylated asparag... |
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Pharmacokinetics of the new progestogens and influence of gestodene and desogestrel on ethinylestradiol metabolism.
Contraception 55(5) , 273-82, (1997) The purpose of the present report is to summarize the most important pharmacokinetic features of the new progestogens. In addition, the question of whether or not gestodene, in comparison to desogestrel, has an influence on the pharmacokinetics of ethinylestr... |
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Effects on hemostatic variables of desogestrel- and gestodene-containing oral contraceptives in comparison with levonorgestrel-containing oral contraceptives: a review.
Am. J. Obstet. Gynecol. 179(3 Pt 2) , S51-61, (1998) In some studies third-generation oral contraceptives have been reported to be associated with a higher risk of venous thromboembolism than are second-generation oral contraceptives, whereas recent, more refined studies have not confirmed this. The reasons for... |
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Desogestrel, norgestimate, and gestodene: the newer progestins.
Ann. Pharmacother. 29(7-8) , 736-42, (1995) To review and compare the newer progestins desogestrel, norgestimate, and gestodene with regard to chemistry, pharmacokinetics, efficacy, and tolerability.Primary literature on desogestrel, norgestimate, and gestodene was identified from a comprehensive MEDLI... |
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Newer non-oral hormonal contraception.
BMJ 346 , f341, (2013)
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Combined oral contraception with desogestrel/ethinyl estradiol: tolerability profile.
Am. J. Obstet. Gynecol. 168(3 Pt 2) , 1028-33, (1993) Since their introduction nearly 30 years ago, oral contraceptives have been widely researched regarding their contraceptive and noncontraceptive effects. With proper usage, oral contraceptives provide highly effective contraception. In addition, oral contrace... |
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Developments in contraception: a comprehensive review of Desogen (desogestrel and ethinyl estradiol).
Contraception 57(5 Suppl) , 1S-27S, (1998)
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