6-Hydroxy-2-naphthonitrile
6-Hydroxy-2-naphthonitrile structure
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Common Name | 6-Hydroxy-2-naphthonitrile | ||
|---|---|---|---|---|
| CAS Number | 52927-22-7 | Molecular Weight | 169.179 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 383.1±15.0 °C at 760 mmHg | |
| Molecular Formula | C11H7NO | Melting Point | 165.5-170.5 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 185.5±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis and structure-activity study of protease inhibitors. V. Chemical modification of 6-amidino-2-naphthyl 4-guanidinobenzoate.
Chem. Pharm. Bull. 41(1) , 117-25, (1993) By developing 6-amidino-2-naphthyl 4-guanidinobenzoate (I, FUT-175) as a basic structure, its various derivatives were synthesized and their inhibitory activities on trypsin, plasmin, kallikrein, thrombin, C1r and C1s as well as on complement-mediated hemolys... |
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Exploration of the active site of β4GalT7: modifications of the aglycon of aromatic xylosides.
Org. Biomol. Chem. 13(11) , 3351-62, (2015) Proteoglycans (PGs) are macromolecules that consist of long linear polysaccharides, glycosaminoglycan (GAG) chains, covalently attached to a core protein by the carbohydrate xylose. The biosynthesis of GAG chains is initiated by xylosylation of the core prote... |
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Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors.
Bioorg. Med. Chem. 18(13) , 4601-5, (2010) Nine newly 6-cyano-2-naphthyl substituted diarylpyrimidines (DAPY) were synthesized as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. The antiviral and cytotoxicity evaluation indicated that these compounds displayed strong... |
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Minor groove binding compounds that jump a gc base pair and bind to adjacent AT base pair sites.
Biochemistry 48(7) , 1573-83, (2009) Most A/T specific heterocyclic diamidine derivatives need at least four A/T base pairs for tight binding to the DNA minor groove. Addition of a GC base pair to A/T sequences typically causes a large decrease in binding constant. The ability to target biologic... |
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Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 1. The selection of naphthalene derivatives.
Chem. Pharm. Bull. 47(12) , 1685-93, (1999) The synthesis and design using molecular modeling techniques for non-peptide, low molecular weight novel fibrinogen receptor (glycoprotein IIb/IIIa: Gp IIb/IIIa) antagonists, is reported. We used a highly potent serine protease inhibitor, Nafamostat, having a... |
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Doping of Polyaniline with 6-Cyano-2-naphthol. Das D, et al.
J. Phys. Chem. B 118(45) , 12993-13001, (2014)
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Ultrafast excited-state proton transfer from cyano-substituted 2-naphthols.
J. Phys. Chem. A 101(25) , 4602-4605, (1997)
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ssDNA templated assembly of oligonucleotides and bivalent naphthalene guests. Janssen PGA, et al.
Soft Matter 6(7) , 1494-1502, (2010)
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