1-Bromo-2-isocyanatobenzene
1-Bromo-2-isocyanatobenzene structure
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Common Name | 1-Bromo-2-isocyanatobenzene | ||
|---|---|---|---|---|
| CAS Number | 1592-00-3 | Molecular Weight | 198.017 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 281.6±0.0 °C at 760 mmHg | |
| Molecular Formula | C7H4BrNO | Melting Point | N/A | |
| MSDS | USA | Flash Point | 92.2±22.6 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Selective synthesis of a [3]rotaxane consisting of size-complementary components and its stepwise deslippage.
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Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development.
Bioorg. Med. Chem. Lett. 16(12) , 3287-91, (2006) Small molecule antagonists of the vanilloid receptor TRPV1 (also known as VR1) are disclosed. Pyrrolidinyl ureas such as 8 and 15 (SB-705498) emerged as lead compounds following optimisation of the previously described urea SB-452533. Pharmacological studies ... |
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Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor.
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