(S)-SNAP 5114
(S)-SNAP 5114 structure
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Common Name | (S)-SNAP 5114 | ||
|---|---|---|---|---|
| CAS Number | 157604-55-2 | Molecular Weight | 505.60 | |
| Density | 1.175g/cm3 | Boiling Point | 643.9ºC at 760mmHg | |
| Molecular Formula | C30H35NO6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 343.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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GABA transporter heterogeneity: pharmacology and cellular localization.
Neurochem. Int. 29 , 335, (1996) gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. GABA is cleared from the synaptic cleft by specific, high-affinity, sodium- and chloride-dependent transporters, which are thought to be located on presynaptic ter... |
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GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors.
Neuropharmacology 39 , 2399-2407, (2000) The present study examines the effect of tiagabine (a selective inhibitor of GABA transporter 1, GAT-1), SNAP-5114 (a semi-selective inhibitor of rat GAT-3/mouse GAT4) and NNC 05-2045 (a non-selective GABA uptake inhibitor) in modulating GABA levels in the hi... |
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GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii.
PLoS Pathog. 8 , e1003051, (2012) During acute infection in human and animal hosts, the obligate intracellular protozoan Toxoplasma gondii infects a variety of cell types, including leukocytes. Poised to respond to invading pathogens, dendritic cells (DC) may also be exploited by T. gondii fo... |