5-(N,N-Dimethyl)amiloride hydrochloride
5-(N,N-Dimethyl)amiloride hydrochloride structure
|
Common Name | 5-(N,N-Dimethyl)amiloride hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1214-79-5 | Molecular Weight | 257.68 | |
| Density | 1.68g/cm3 | Boiling Point | 543.6ºC at 760mmHg | |
| Molecular Formula | C8H12ClN7O | Melting Point | 216-217°C(lit.) | |
| MSDS | USA | Flash Point | 282.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin.
Int. J. Pharm. 478(2) , 745-52, (2015) Inhibitors against multidrug resistance (MDR) efflux transporters have failed in most clinical settings due to unfavorable pharmacokinetic interactions with co-administered anti-cancer drug and their inherent toxicities. Nanoparticles (NPs) have shown potenti... |
|
|
Hygroscopic and phase transition properties of alkyl aminium sulfates at low relative humidities.
Phys. Chem. Chem. Phys. 17 , 19789-96, (2015) Alkyl aminium sulfates (AASs) can affect the physicochemical properties of atmospheric aerosols such as hygroscopicity. Previous laboratory experiments have shown that the water content in AAS bulk solutions is higher than in aqueous ammonium sulfate solution... |
|
|
Exposure to mercury and Aroclor 1268 congeners in least terns (Sternula antillarum) in coastal Georgia, USA.
Environ. Sci. Process. Impacts 17 , 1424-32, (2015) Concentrations of total mercury and the rare PCB mixture Aroclor 1268 in least terns (Sternula antillarum), a colonially-nesting, piscivorous seabird, in the Turtle River estuary and other coastal sites in Georgia, USA, were investigated. The Turtle River est... |
|
|
Selective removal of phosphate for analysis of organic acids in complex samples.
J. Chromatogr. A. 1388 , 1-8, (2015) Accurate quantitation of compounds in samples of biological origin is often hampered by matrix interferences one of which occurs in GC-MS analysis from the presence of highly abundant phosphate. Consequently, high concentrations of phosphate need to be remove... |
|
|
Dimethyl adipimidate/Thin film Sample processing (DTS); A simple, low-cost, and versatile nucleic acid extraction assay for downstream analysis.
Sci. Rep. 5 , 14127, (2015) Sample processing, especially that involving nucleic acid extraction, is a prerequisite step for the isolation of high quantities of relatively pure DNA for downstream analyses in many life science and biomedical engineering studies. However, existing methods... |
|
|
Synthesis and In Vitro Evaluation of Thiolated Carrageenan.
J. Pharm. Sci. 104 , 2523-30, (2015) The aim of this study was to generate and characterize a thiolated carrageenan. Thiolated carrageenan (carrageenan-SH) was synthesized from kappa (κ)- and iota (ι)-carrageenan by bromine replacement of the hydroxyl moieties followed by substitution to thiol g... |
|
|
Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.
J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014) Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional... |
|
|
¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS ONE 10(3) , e0120950, (2015) Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information of curcumin on hyperlipidemia models has been revealed, which may provide us an insight into the underly... |
|
|
QUANTITY: An Isobaric Tag for Quantitative Glycomics.
Sci. Rep. 5 , 17585, (2015) Glycan is an important class of macromolecules that play numerous biological functions. Quantitative glycomics--analysis of glycans at global level--however, is far behind genomics and proteomics owing to technical challenges associated with their chemical pr... |
|
|
Inter- and intra-organ spatial distributions of sea star saponins by MALDI imaging.
Anal. Bioanal. Chem 407 , 8813-24, (2015) Saponins are secondary metabolites that are abundant and diversified in echinoderms. Mass spectrometry is increasingly used not only to identify saponin congeners within animal extracts but also to decipher the structure/biological activity relationships of t... |