Tramadol hydrochloride
Tramadol hydrochloride structure
|
Common Name | Tramadol hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 36282-47-0 | Molecular Weight | 299.836 | |
| Density | N/A | Boiling Point | 388.1ºC at 760 mmHg | |
| Molecular Formula | C16H26ClNO2 | Melting Point | 178-181ºC | |
| MSDS | Chinese USA | Flash Point | 188.5ºC | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
|
Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.
J. Chromatogr. A. 1418 , 140-9, (2015) The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of 37 micropollutants including Priority Substances (Directiv... |
|
|
Simultaneous Determination of Tramadol and its Metabolite in Human Plasma by GC/MS.
J. AOAC Int. 98(1) , 56-61, (2015) A simple and sensitive GC/MS method for the determination of tramadol and its metabolite (O-desmethyltramadol) in human plasma was developed and validated. Medazepam was used as an internal standard. The calibration curves were linear (r=0.999) over tramadol ... |
|
|
Simultaneous Determination of Tramadol and Its Metabolite in Human Urine by the Gas Chromatography-Mass Spectrometry Method.
J. Chromatogr. Sci. 53 , 1037-43, (2015) A sensitive and efficient method was developed for determination of tramadol and its metabolite (O-desmethyltramadol) in human urine by gas chromatography-mass spectrometry. Tramadol, O-desmethyltramadol and medazepam (internal standard) were extracted from h... |
|
|
Rhesus monkey is a new model of secondary lymphedema in the upper limb.
Int. J. Clin. Exp. Pathol. 7(9) , 5665-73, (2014) This study is to establish the rhesus monkey model of lymphedema in the upper limbs, and assess the suitability of this model.An animal model of lymphedema was established by the combined irradiation and surgical techniques in the upper limbs of these rhesus ... |
|
|
Simultaneous determination of tramadol and O-desmethyltramadol in human plasma using HPLC-DAD.
J. Chromatogr. Sci. 52(10) , 1186-92, (2014) A sensitive and accurate method for the extraction and quantification of tramadol (T) and its active metabolite, O-desmethyltramadol (ODT) in human plasma with high-performance liquid chromatography-diode array detection was developed and validated. The analy... |
|
|
PHARMACOKINETICS OF TRAMADOL HYDROCHLORIDE AND ITS METABOLITE O-DESMETHYLTRAMADOL FOLLOWING A SINGLE, ORALLY ADMINISTERED DOSE IN CALIFORNIA SEA LIONS (ZALOPHUS CALIFORNIANUS).
J. Zoo Wildl. Med. 46 , 476-81, (2015) Tramadol is a synthetic, centrally acting, opiate-like analgesic that is structurally related to codeine and morphine. The objective of this study was to determine the pharmacokinetics of tramadol hydrochloride and its major active metabolite O-desmethyltrama... |
|
|
Biopharmaceutical evaluation of new slow release tablets obtained by hot tableting of coated pellets with tramadol hydrochloride.
Acta Pol. Pharm. 71(5) , 813-20, (2014) This study was aimed at a biopharmaceutical evaluation of a new oral dosage form of tramadol hydrochloride (TH)--slow release tablets obtained by hot tableting of coated pellets, 100 mg (TP), compared to the conventional slow release tablets, Tramal Retard, 1... |
|
|
In vitro - in vivo evaluation of a new oral dosage form of tramadol hydrochloride--controlled-release capsules filled with coated pellets.
Acta Pol. Pharm. 71(3) , 469-75, (2014) The aim of this study was an in vitro - in vivo evaluation of a new oral dosage form of tramadol hydrochloride (TH), controlled-release capsules filled with coated pellets, 100 mg (TC), compared to the sustained release tablets, Tramal Retard, 100 mg (TR). In... |
|
|
Pharmacokinetics of tramadol and o-desmethyltramadol in goats after intravenous and oral administration.
J. Vet. Pharmacol. Ther. 31(1) , 45-51, (2008) The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of these substances following intravenous (i.v.) and oral (p.o.... |
|
|
Detection and quantification of the opioid tramadol in urine using surface enhanced Raman scattering.
Analyst 140 , 5965-70, (2015) There is an on going requirement for the detection and quantification of illicit substances. This is in particular the case for law enforcement where portable screening methods are needed and there has been recent interest in breath tests for a range of narco... |