2,2-Dimethylmalonic acid
2,2-Dimethylmalonic acid structure
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Common Name | 2,2-Dimethylmalonic acid | ||
|---|---|---|---|---|
| CAS Number | 595-46-0 | Molecular Weight | 132.115 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 310.2±25.0 °C at 760 mmHg | |
| Molecular Formula | C5H8O4 | Melting Point | 191-193 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 155.6±19.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Targeted metabolomics in the expanded newborn screening for inborn errors of metabolism.
Mol. Biosyst. 11 , 1525-35, (2015) Inborn errors of metabolism are genetic disorders due to impaired activity of enzymes, transporters, or cofactors resulting in accumulation of abnormal metabolites proximal to the metabolic block, lack of essential products or accumulation of by-products. Man... |
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Method development in quantitative NMR towards metrologically traceable organic certified reference materials used as (31)P qNMR standards.
Anal. Bioanal. Chem 407 , 3115-3123, (2015) Quantitative nuclear magnetic resonance (qNMR) spectroscopy is employed by an increasing number of analytical and industrial laboratories for the assignment of content and quantitative determination of impurities. Within the last few years, it was demonstrate... |
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Using high-performance ¹H NMR (HP-qNMR®) for the certification of organic reference materials under accreditation guidelines--describing the overall process with focus on homogeneity and stability assessment.
J. Pharm. Biomed. Anal. 93 , 102-110, (2014) Quantitative NMR spectroscopy (qNMR) is gaining interest across both analytical and industrial research applications and has become an essential tool for the content assignment and quantitative determination of impurities. The key benefits of using qNMR as me... |
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Application of capillary electrophoresis with laser-induced fluorescence detection for routine determination of methylmalonic acid in human serum.
Anal. Chem. 67(5) , 812-9, (1995) Methylmalonic acid (MMA) in serum is an established marker of cobalamin deficiency. MMA and other short-chain dicarboxylic acids react with 1-pyrenyldiazomethane to form stable, highly fluorescent 1-pyrenylmethyl monoesters. We have analyzed these esters in h... |
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A low-barrier hydrogen bond in the catalytic triad of serine proteases.
Science 264(5167) , 1927-30, (1994) Spectroscopic properties of chymotrypsin and model compounds indicate that a low-barrier hydrogen bond participates in the mechanism of serine protease action. A low-barrier hydrogen bond between N delta 1 of His57 and the beta-carboxyl group of Asp102 in chy... |
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Ion-trap detection of volatile organic compounds in alveolar breath.
Clin. Chem. 38(1) , 60-5, (1992) We describe a method for the collection and microanalysis of the volatile organic compounds in human breath. A transportable apparatus supplies subjects with purified air and samples their alveolar breath; the volatile organic compounds are captured in an ads... |
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Anaerobic mineralization of quaternary carbon atoms: isolation of denitrifying bacteria on dimethylmalonate.
Appl. Environ. Microbiol. 65(8) , 3319-24, (1999) The microbial capacity to degrade simple organic compounds with quaternary carbon atoms was demonstrated by enrichment and isolation of five denitrifying strains on dimethylmalonate as the sole electron donor and carbon source. Quantitative growth experiments... |
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Electron spin-lattice relaxation in radicals containing two methyl groups, generated by gamma-irradiation of polycrystalline solids.
J. Magn. Reson. 159(2) , 195-206, (2002) The effects of methyl rotation on electron spin-lattice relaxation times were examined by pulsed electron paramagnetic resonance for the major radicals in gamma-irradiated polycrystalline alpha-amino isobutyric acid, dimethyl-malonic acid, and L-valine. The d... |
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Using high-performance quantitative NMR (HP-qNMR) for certifying traceable and highly accurate purity values of organic reference materials with uncertainties <0.1 % Weber, M., Hellriegel, C., Rueck, A., Sauermoser, R., and Wuethrich, J.
Accred. Qual. Assur. 18 , 91-98, (2013)
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