1-Phenylbutan-1-one

1-Phenylbutan-1-one Structure
1-Phenylbutan-1-one structure
Common Name 1-Phenylbutan-1-one
CAS Number 495-40-9 Molecular Weight 148.202
Density 1.0±0.1 g/cm3 Boiling Point 228.5±0.0 °C at 760 mmHg
Molecular Formula C10H12O Melting Point 11-13 °C(lit.)
MSDS Chinese USA Flash Point 88.9±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Repetitive injection method: a tool for investigation of injection zone formation and its compression in microfluidic liquid chromatography.

J. Chromatogr. A. 1381 , 110-7, (2015)

Sample introduction in microfluidic liquid chromatography often generates wide zones rather than peaks, especially when a large sample volume (relative to column volume) is injected. Formation of wide injection zones can be further amplified when the sample i...

Wide injection zone compression in gradient reversed-phase liquid chromatography.

J. Chromatogr. A. 1390 , 86-94, (2015)

Chromatographic zone broadening is a common issue in microfluidic chromatography, where the sample volume introduced on column often exceeds the column void volume. To better understand the propagation of wide chromatographic zones on a separation device, a s...

Efficiency of short, small-diameter columns for reversed-phase liquid chromatography under practical operating conditions.

J. Chromatogr. A. 1383 , 47-57, (2015)

Prototype small-size (1.0mm I.D., 5cm long) columns for reversed-phase HPLC were evaluated in relation to instrument requirements. The performance of three types of columns, monolithic silica and particulate silica (2μm, totally porous and 2.6μm, core-shell p...

Lipophilicity of porphyrins and their retention in IAM, C8-C18 and HILIC chromatographic systems.

J. Pharm. Biomed. Anal. 114 , 227-40, (2015)

Porphyrins are a class of photosensitizers used in photodynamic therapy (PDT). Understanding the interaction of porphyrins with membrane cells components is important in order to improve this therapy. Many analytical methods can be used for this aim. High per...

Effect of gradient steepness on the kinetic performance limits and peak compression for reversed-phase gradient separations of small molecules.

J. Chromatogr. A. 1409 , 152-8, (2015)

The effect of gradient steepness on the kinetic performance limits and peak compression effects has been assessed in gradient mode for the separation of phenol derivatives using columns packed with 2.6μm core-shell particles. The effect of mobile-phase veloci...

Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.

Bioorg. Med. Chem. Lett. 15 , 3241-6, (2005)

SR protein-specific kinase-1 (SRPK-1) has been identified as a validated target for hepatitis B virus (HBV). A series of novel tricyclic quinoxaline derivatives was designed and synthesised as potential kinase inhibitory antiviral agents and was found to be a...

Ketalization of phosphonium ions by 1,4-dioxane: selective detection of the chemical warfare agent simulant DMMP in mixtures using ion/molecule reactions.

J. Am. Soc. Mass Spectrom. 14(3) , 182-8, (2003)

Phosphonium ions CH(3)P(O)OCH(3)(+) (93 Th) and CH(3)OP(O)OCH(3)(+) (109 Th) react with 1,4-dioxane to form unique cyclic ketalization products, 1,3,2-dioxaphospholanium ions. By contrast, a variety of other types of ions having multiple bonds, including the ...

Butyrophenone influences on the opiate receptor.

Eur. J. Pharmacol. 36(1) , 231-5, (1976)

Interaction of neuroleptic drugs with the opiate receptors was investigated by inhibition of the stereospecific binding of 3H-naloxone. Benperidol and pimozide, with IC50's of 0.3-0.5 muM, were more potent than the classical opiates meperidine and propoxyphen...

Using the column wall itself as resistive heater for fast temperature gradients in liquid chromatography.

J. Chromatogr. A. 1420 , 129-34, (2015)

A new system is proposed for applying fast temperature gradients in liquid chromatography. It consists of a 0.7 mm × 150 mm fused-silica column coated with a 50 μm Nickel-layer, which is connecting with a power source and a temperature control system to perfo...

Impact of the column hardware volume on resolution in very high pressure liquid chromatography non-invasive investigations.

J. Chromatogr. A. 1420 , 54-65, (2015)

The impact of the column hardware volume (≃ 1.7 μL) on the optimum reduced plate heights of a series of short 2.1 mm × 50 mm columns (hold-up volume ≃ 80-90 μL) packed with 1.8 μm HSS-T3, 1.7 μm BEH-C18, 1.7 μm CSH-C18, 1.6 μm CORTECS-C18+, and 1.7 μm BEH-C4 ...