1,2-Dibromobenzene
1,2-Dibromobenzene structure
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Common Name | 1,2-Dibromobenzene | ||
|---|---|---|---|---|
| CAS Number | 583-53-9 | Molecular Weight | 235.904 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 225.4±13.0 °C at 760 mmHg | |
| Molecular Formula | C6H4Br2 | Melting Point | 4-6 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 91.7±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.
Eur. J. Med. Chem. 43 , 714-40, (2008) Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors.... |
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An advantageous route to oxcarbazepine (trileptal) based on palladium-catalyzed arylations free of transmetallating agents.
Org. Lett. 7(22) , 4787-9, (2005) [reaction: see text] A new route to oxcarbazepine (Trileptal), the most widely prescribed antiepileptic drug, starting from commercially available 2'-aminoacetophenone and 1,2-dibromobenzene, is reported. The sequentially accomplished key steps are palladium-... |
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Hepatotoxicity of brominated benzenes: relationship between chemical structure and hepatotoxic effects in acute intoxication of mice.
Arch. Toxicol. 72(2) , 97-103, (1998) Brominated benzenes appear in the environment and human tissues. Their detection in the environment may be as a result of their usage, e.g. hexabromobenzene (HBB), and as products of HBB degradation or metabolism. The aim of this study was to compare liver im... |
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Comparison of tissue distribution and metabolism of 1,2- and 1,4-dibromobenzenes in female rats.
Int. J. Occup. Med. Environ. Health 15(4) , 375-83, (2002) The distribution, excretion and metabolism of 1,4-dibromobenzene (1,4-DBB) and 1,2-dibromobenzene (1,2-DBB), following a single intraperitoneal administration to female Wistar rats, were investigated using radiotracer 3H and GC-MS technique. The maximum level... |
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Comparison of hepatotoxicity of 1,2-, 1,3- and 1,4-dibromobenzenes: the dynamics of changes of selected parameters of liver necrosis in acute poisoning in mice.
J. Appl. Toxicol. 16(1) , 35-41, (1996) Various doses of dibromobenzene isomers (1,2-dBB, 1,3-dBB, 1,4-dBB) were administered (i.p.) to BALB mice. The levels of reduced glutathione (GSH) and malondialdehyde (MDA) in the liver, and glutamate-pyruvate transaminase (GPT) (EC.2.6.1.2) gamma-glutamyltra... |
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Halogen-metal exchange in 1,2-dibromobenzene and the possible intermediacy of 1,2-dilithiobenzene.
J. Org. Chem. 72(25) , 9750-2, (2007) The one-step high-yield synthesis of 1,2-bis(trimethylsilyl)benzene from 1,2-dibromobenzene using tert-butyllithium and trimethylsilyltriflate is reported. A mechanistic investigation shows that 1,2-dilithiobenzene is not an intermediate in this reaction; the... |
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Vibrational spectroscopic investigation (FT-IR and FT-Raman) on 1,2-dibromobenzene by HF and hybrid (LSDA and B3LYP) calculations.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 86 , 449-55, (2012) The FT-IR and FT-Raman spectra of the compound 1,2-dibromobenzene have been recorded in the region 4000-100cm(-1). The vibrational analysis has been made using HF and DFT (B3LYP and LSDA) level of theory by employing 6-31 +G (d, p) and 6-311 ++G (d, p) basis ... |