L-(+)-Leucinol
L-(+)-Leucinol structure
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Common Name | L-(+)-Leucinol | ||
|---|---|---|---|---|
| CAS Number | 7533-40-6 | Molecular Weight | 117.189 | |
| Density | 0.917 | Boiling Point | 208-210 ºC | |
| Molecular Formula | C6H15NO | Melting Point | 66 - 70ºC | |
| MSDS | Chinese USA | Flash Point | 90 ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Pharmaceuticals and Surfactants from Alga-Derived Feedstock: Amidation of Fatty Acids and Their Derivatives with Amino Alcohols.
ChemSusChem 8 , 2670-80, (2015) Amidation of renewable feedstocks, such as fatty acids, esters, and Chlorella alga based biodiesel, was demonstrated with zeolites and mesoporous materials as catalysts and ethanolamine, alaninol, and leucinol. The last two can be derived from amino acids pre... |
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Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation.
Chemistry 9(22) , 5567-80, (2003) Four new chiral bis(amino alcohol)oxalamides (1-4: amino alcohol=leucinol, valinol, phenylglycinol, and phenylalaninol, respectively) have been prepared as low-molecular-weight organic gelators. Their gelation properties towards various organic solvents and m... |
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A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.
Chirality 23(4) , 349-53, (2011) A new colorimetric chiral sensor material consisting of three different functional sites such as chromophore (2,4-dinitrophenylazophenol dye), binding site (crown ether), and chiral barrier (3,3'-diphenyl-1,1'-binaphthyl group) was prepared and applied to the... |
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Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation.
J. Med. Chem. 35 , 1259, (1992) Derivatives of amino acids bearing various zinc-coordinating moieties (SH, COOH, CONHOH, and PO3H2) were synthesized and tested for their ability to inhibit aminopeptidase N (APN). Among them, beta-amino thiols were found to be the most efficient with IC50's ... |
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Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex.
J. Med. Chem. 35 , 2939, (1992) A series of substrate analogue inhibitors of pancreatic phospholipase A2 has been designed and synthesized. The compounds were tested in a novel dual-screening system based on parallel assays with monomeric and micellar substrates. Intermolecular nuclear Over... |
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Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine protease.
J. Med. Chem. 52 , 1370-1379, (2009) The hepatitis C virus (HCV) infection is a leading cause of chronic liver disease. The moderate efficacy along with side effects of the current pegylated interferon and ribavirin combination therapy underscores the need for more effective and safer new treatm... |
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Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.
Science 307(5716) , 1776-8, (2005) Recognizing a deficiency of indispensable amino acids (IAAs) for protein synthesis is vital for dietary selection in metazoans, including humans. Cells in the brain's anterior piriform cortex (APC) are sensitive to IAA deficiency, signaling diet rejection and... |
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Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species.
J. Biol. Chem. 277(29) , 26057-65, (2002) Aminopeptidases are emerging as exciting novel drug targets and vaccine candidates in parasitic infections. In this study, we describe for the first time an aminopeptidase from three highly pathogenic Leishmania species. Intronless genes encoding a leucyl ami... |
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Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
J. Cell. Biochem. 79(3) , 427-41, (2000) Enhanced phosphorylation of the ribosomal protein s6 kinase, p70(s6k), and the translational repressor, 4E-BP1, are associated with either insulin-induced or amino acid-induced protein synthesis. Hyperphosphorylation of p70(s6k) and 4E-BP1 in response to insu... |
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Enantiospecific wetting.
J. Am. Chem. Soc. 132(51) , 18051-3, (2010) Experiments have shown that enantiospecificity can be important in wetting. Measurements of droplet contact angles can be used to estimate the energy of enantiomeric discrimination. |