3-Methoxycatechol

3-Methoxycatechol Structure
3-Methoxycatechol structure
Common Name 3-Methoxycatechol
CAS Number 934-00-9 Molecular Weight 140.137
Density 1.3±0.1 g/cm3 Boiling Point 268.1±0.0 °C at 760 mmHg
Molecular Formula C7H8O3 Melting Point 38-43 °C(lit.)
MSDS Chinese USA Flash Point 119.5±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Free-Radical-Scavenging, Antityrosinase, and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavones.

Chem. Biodivers. 12 , 963-79, (2015)

In this study, we examined the potential of synthetic isoflavones for application in cosmeceuticals. Twenty-five isoflavones were synthesized and their capacities of free-radical-scavenging and mushroom tyrosinase inhibition, as well as their impact on cell v...

Prediction model based on decision tree analysis for laccase mediators.

Enzyme Microb. Technol. 52(1) , 68-76, (2013)

A Structure Activity Relationship (SAR) study for laccase mediator systems was performed in order to correctly classify different natural phenolic mediators. Decision tree (DT) classification models with a set of five quantum-chemical calculated molecular des...

Altering toluene 4-monooxygenase by active-site engineering for the synthesis of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone.

J. Bacteriol. 186(14) , 4705-13, (2004)

Wild-type toluene 4-monooxygenase (T4MO) of Pseudomonas mendocina KR1 oxidizes toluene to p-cresol (96%) and oxidizes benzene sequentially to phenol, to catechol, and to 1,2,3-trihydroxybenzene. In this study T4MO was found to oxidize o-cresol to 3-methylcate...

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists.

Pharmaceuticals (Basel.) 6 , 500-9, (2013)

Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-met...

Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model.

Cancer Res. 53(1) , 32-7, (1993)

Effects of simultaneous treatment with NaNO2 and butylated hydroxyanisole, catechol, or 3-methoxycatechol were examined in a rat multiorgan carcinogenesis model. Groups of 15 animals were given a single i.p. injection of 100 mg/kg of body weight diethylnitros...

Effects of combined treatment with phenolic compounds and sodium nitrite on two-stage carcinogenesis and cell proliferation in the rat stomach.

Jpn. J. Cancer Res. 85(1) , 17-25, (1994)

The effects of combined treatment with NaNO2 and phenolic compounds on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) stomach carcinogenesis were investigated in F344 rats. In the first experiment, groups of 15-20 male rats were treated with an intragastric dose...

Effects of sodium nitrite and catechol or 3-methoxycatechol in combination on rat stomach epithelium.

Jpn. J. Cancer Res. 81(9) , 857-61, (1990)

The effects of sodium nitrite (NaNO2) and catechol or 3-methoxycatechol in combination were examined in male F344 rats. Animals were treated with 0.3% NaNO2 in the drinking water and 0.8% catechol or 2% 3-methoxycatechol in powdered diet for 24 weeks. While c...

A novel catechol-based universal support for oligonucleotide synthesis.

J. Org. Chem. 72(26) , 9875-80, (2007)

A novel universal support for deoxyribo- and ribonucleic acid synthesis has been developed. The support, constructed from 1,4-dimethoxycatechol, represents an improvement over existing universal supports because of its ability to cleave and deprotect under mi...