4-Hexylresorcinol
4-Hexylresorcinol structure
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Common Name | 4-Hexylresorcinol | ||
|---|---|---|---|---|
| CAS Number | 136-77-6 | Molecular Weight | 194.270 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 329.5±12.0 °C at 760 mmHg | |
| Molecular Formula | C12H18O2 | Melting Point | 65-67 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 155.2±14.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Toxicol. Mech. Methods 18 , 217-27, (2008) ABSTRACT Drug-induced phospholipidosis (PL) is a condition characterized by the accumulation of phospholipids and drug in lysosomes, and is found in a variety of tissue types. PL is frequently manifested in preclinical studies and may delay or prevent the dev... |
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Preparation, characterization, and preliminary antibrowning evaluations of norartocarpetin microemulsions.
J. Agric. Food Chem. 63(5) , 1615-21, (2015) Norartocarpetin is a flavone widely distributed in Moraceae plants with strong tyrosinase inhibitory activity. However, its poor solubility in aqueous systems and in food grade solvents (oils) limits its extensive applications. The aim of this study was to im... |
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Effects of 4-hexylresorcinol on the phenoloxidase from Hyphantria cunea (Lepidoptera: Arctiidae): In vivo and in vitro studies.
Insect Sci. 22 , 639-50, (2015) Insecticidal effects of 4-hexylresorcinol, a phenoloxidase (PO) inhibitor, were determined on Hyphantria cunea (Drury) under laboratory conditions. The LC50 for the 15-d-old larvae was estimated to be 2.95 g/L after 96 h exposure. The activities of glutathion... |
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Tyrosinase-Catalyzed Hydroxylation of 4-Hexylresorcinol, an Antibrowning and Depigmenting Agent: A Kinetic Study.
J. Agric. Food Chem. 63 , 7032-40, (2015) 4-Hexylresorcinol (HR) is a compound used in the food and cosmetic industries as an antibrowning and lightening agent. Its use is mainly attributed to its inhibitory effect on the enzyme tyrosinase. However, the enzyme hydroxylates HR to an o-diphenol, which ... |
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PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.
Bioorg. Med. Chem. Lett. 19 , 36-9, (2009) In this work, the PEG-immobilization and the liquid phase synthesis of some coumarins derived from cardol are presented. Some preliminary results on their tyrosinase inhibitory activity are also included. |
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Comparison of the simple cyclic voltammetry (CV) and DPPH assays for the determination of antioxidant capacity of active principles.
Molecules 17(5) , 5126-38, (2012) Antioxidant activity of a number of small (low molecular weight) natural compounds found in spices, condiments or drugs (gallic acid, sesamol, eugenol, thymol, carvacrol, vanillin, salicylaldehyde, limonene, geraniol, 4-hexylresorcinol, etc.) has been evaluat... |
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Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI.
PLoS ONE 8(2) , e58010, (2013) DNA topoisomerases are highly exploited targets for antimicrobial drugs. The spread of antibiotic resistance represents a significant threat to public health and necessitates the discovery of inhibitors that target topoisomerases in novel ways. However, the t... |
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Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus.
Comp. Biochem. Physiol. B Biochem. Mol. Biol. 163(3-4) , 303-8, (2012) Inhibitors of phenoloxidase are used routinely to characterise the structural and functional properties of phenoloxidases. Hemocyanin-derived phenoloxidase activity is also sensitive to standard phenoloxidase inhibitors. In this study, we characterise the eff... |
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[Long-term preservation of DNA in aqueous solutions in the presence of the chemical analogues of microbial autoregulators].
Mikrobiologiia 75(5) , 662-9, (2006) The fact of long-term preservation of the physicochemical properties of DNA molecules in aqueous solutions in complexes with methylresorcinol, hexylresorcinol, and tyrosol, the chemical analogues of microbial autoregulators (d1 factors) from the group of alky... |
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[Influence of chemical analogues of microbial autoregulators on the sensitivity of DNA to UV radiation].
Mikrobiologiia 75(5) , 654-61, (2006) We established that chemical analogues of alkylhydroxybenzenes (AHB), belonging to alkylresorcinols and functioning as microbial autoregulatory d1 factors, enhance the UV resistance of various DNA molecules of different origin and conformation. These include ... |