Bioorganic & Medicinal Chemistry Letters 2009-01-01

PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.

Graziella Tocco, Antonella Fais, Gabriele Meli, Michela Begala, Gianni Podda, M Benedetta Fadda, Marcella Corda, Orazio A Attanasi, Paolino Filippone, Stefano Berretta

Index: Bioorg. Med. Chem. Lett. 19 , 36-9, (2009)

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Abstract

In this work, the PEG-immobilization and the liquid phase synthesis of some coumarins derived from cardol are presented. Some preliminary results on their tyrosinase inhibitory activity are also included.