Adipostatin A

Modify Date: 2024-01-03 17:06:48

Adipostatin A Structure
Adipostatin A structure
Common Name Adipostatin A
CAS Number 3158-56-3 Molecular Weight 320.50900
Density 0.96g/cm3 Boiling Point 452.5ºC at 760mmHg
Molecular Formula C21H36O2 Melting Point N/A
MSDS Chinese USA Flash Point 195.5ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of Adipostatin A


5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 µM. Adipostatin A shows good larvicidal activity against Aedes aegypti[1][2].

 Names

Name cardol
Synonym More Synonyms

 Adipostatin A Biological Activity

Description 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 µM. Adipostatin A shows good larvicidal activity against Aedes aegypti[1][2].
Related Catalog
In Vitro 5-Pentadecylresorcinol (Adipostatin A) prevents triglyceride accumulation in 3T3-L1 cells at a concentration of the microM level[1].
References

[1]. Tsuge, et al. Adipostatins A and B, new inhibitors of glycerol-3-phosphate dehydrogenase. J Antibiot (Tokyo). 1992 Jun;45(6):886-91.

[2]. Micheline Soares Costa Oliveira, et al. Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents. Acta Trop. 2011 Mar;117(3):165-70.

 Chemical & Physical Properties

Density 0.96g/cm3
Boiling Point 452.5ºC at 760mmHg
Molecular Formula C21H36O2
Molecular Weight 320.50900
Flash Point 195.5ºC
Exact Mass 320.27200
PSA 40.46000
LogP 6.73150
Index of Refraction 1.509
Storage condition 2-8°C

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H317-H318
Precautionary Statements P280-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 41-43
Safety Phrases 26-36/37-39
RIDADR NONH for all modes of transport
HS Code 2907299090

 Synthetic Route

 Customs

HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

 Articles26

More Articles
Quantum mechanical and experimental oxidation studies of pentadecylresorcinol, olivetol, orcinol and resorcinol.

Free Radic. Res. 28(4) , 359-68, (1998)

Resorcinols (pentadecylresorcinol, olivetol, orcinol and resorcinol) exhibit antioxidant properties in liposomal systems. Antioxidant potency depends on the length of the alkyl chain. Pentadecylresorc...

Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis.

Phytochemistry 106 , 156-63, (2014)

Chemical investigation of a sample of propolis originating from North-Western Cameroon led to the isolation of thirteen alk(en)ylphenols (1-13) (inseparable mixture) along with α-amyrin (14), β-amyrin...

PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.

Bioorg. Med. Chem. Lett. 19 , 36-9, (2009)

In this work, the PEG-immobilization and the liquid phase synthesis of some coumarins derived from cardol are presented. Some preliminary results on their tyrosinase inhibitory activity are also inclu...

 Synonyms

1,3-Benzenediol,5-pentadecyl
5-pentadecylbenzene-1,3-diol
1,3-dihydroxy-5-pentadecylbenzene
5-n-pentadecylresorcinol
5-Pentadecyl-1,3-benzenediol
Resorcinol,pentadecyl
RESORCINOL,5-PENTADECYL
Cardol
adipostatin A
5-pentadecylresorcinol