2-Aminopyridine
2-Aminopyridine structure
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Common Name | 2-Aminopyridine | ||
|---|---|---|---|---|
| CAS Number | 504-29-0 | Molecular Weight | 94.115 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 210.6±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H6N2 | Melting Point | 59 °C | |
| MSDS | Chinese USA | Flash Point | 98.7±7.0 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Determination of major sialylated N-glycans and identification of branched sialylated N-glycans that dynamically change their content during development in the mouse cerebral cortex.
Glycoconj. J. 31(9) , 671-83, (2014) Oligosaccharides of glycoproteins expressed on the cell surface play important roles in cell-cell interactions, particularly sialylated N-glycans having a negative charge, which interact with sialic acid-binding immunoglobulin-like lectins (siglecs). The enti... |
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One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br(3) and 2-aminopyridine under solvent-free conditions.
Molecules 17(11) , 13368-75, (2012) One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br(3) and 2-aminopyridine under solvent-free conditions in the presence of Na(2)CO(3), gave the corresponding 2-phenylimidazo[1,2-α]pyridines in excellent yields ranging from 72% to... |
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Synthesis and Characterization of a Novel Phenolic Lipid for Use as Potential Lipophilic Antioxidant and as a Prodrug of Butyric Acid.
J. Oleo Sci. 64 , 845-52, (2015) Ferulic acid was modified to produce a novel phenolipid containing butyl chains. Ferulic acid was esterified with butanol to produce butyl ferulate which was further dihydroxylated followed by esterification with butyric anhydride to produce the phenolipid co... |
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Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity.
J. Med. Chem. 54 , 6482-91, (2011) New synthetic protocol for the preparation of nucleoside 5'-(N-aryl)phosphoramidate monoesters 4 was developed. It consisted of a condensation of the corresponding nucleoside 5'-H-phosphonates with aromatic- or heteroaromatic amines promoted by diphenyl phosp... |
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Synthesis and characterization of binary and ternary complexes of Co(II), Ni(II), Cu(II) and Zn(II) ions based on 4-aminotoluene-3-sulfonic acid.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 105 , 109-24, (2013) Salicylidene (4-aminotoluene-3-sulfonic acid) Schiff base ligand H(2)L, and its binary and ternary Co(II), Ni(II), Cu(II) and Zn(II) complexes using 8-hydroxyquinoline (8-HOqu) and 2-aminopyridine (2-Ampy) as secondary ligands have been synthesised and charac... |
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Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.
Eur. J. Med. Chem. 44 , 2877-87, (2009) A series of new 3-aroylpyrido[1,2-a]pyrimidines were synthesized from aryl methyl ketones in a simple two-step procedure and evaluated as nitric oxide synthases (NOS) inhibitors. In order to perform a structure-activity relationship study, different aroyl gro... |
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Affinity entrapment of oligosaccharides and glycopeptides using free lectin solution.
Anal. Sci. 27(4) , 395, (2011) Two procedures were proposed for the specific recovery of fluorescent derivatives of glycoprotein-derived oligosaccharides and tryptic glycopeptides using certain plant lectins. The first was based on the salting out of oligosaccharide-lectin conjugates with ... |
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Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis.
Oncol. Rep. 28(5) , 1597-605, (2012) The mechanisms responsible for human inflammatory bowel disease remain poorly understood. The pathogenic factors for dextran sulfate sodium (DSS)-induced colitis, one of the experimental animal colitis models, also remain unknown. Furthermore, detailed studie... |
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Iron-catalyzed formation of 2-aminopyridines from diynes and cyanamides.
J. Org. Chem. 77(17) , 7555-63, (2012) Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and a cy... |
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Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
Bioorg. Med. Chem. Lett. 21 , 5778-83, (2011) Heat shock protein 90 (Hsp90) is a molecular chaperone which regulates maturation and stabilization of its substrate proteins, known as client proteins. Many client proteins of Hsp90 are involved in tumor progression and survival and therefore Hsp90 can be a ... |