1-Butaneboronic acid
1-Butaneboronic acid structure
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Common Name | 1-Butaneboronic acid | ||
|---|---|---|---|---|
| CAS Number | 4426-47-5 | Molecular Weight | 101.940 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 189.2±23.0 °C at 760 mmHg | |
| Molecular Formula | C4H11BO2 | Melting Point | 90-92 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 68.2±22.6 °C | |
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Inhibitors of bacterialN-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity
Bioorg. Med. Chem. Lett. 19 , 6350-2, (2009) A screen biased toward compounds containing zinc-binding groups (ZBG’s) delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including l-captopril (IC 50 = 3.3 μM, K i = 1.8 μM). In vitro antimicrobial activity was demonstrated for... |
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n-Alkylboronic acid inhibitors reveal determinants of ligand specificity in the quorum-quenching and siderophore biosynthetic enzyme PvdQ.
Biochemistry 53(42) , 6679-86, (2014) The enzyme PvdQ (E.C. 3.5.1.97) from Pseudomonas aeruginosa is an N-terminal nucleophile hydrolase that catalyzes the removal of an N-myristyl substituent from a biosynthetic precursor of the iron-chelating siderophore pyoverdine. Inhibitors of pyoverdine bio... |
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The use of low-energy collisionally activated dissociation negative-ion tandem mass spectrometry for the characterization of dog and human urinary metabolites of the drug BW 1370U87.
Rapid Commun. Mass Spectrom. 8(3) , 265-73, (1994) Liquid chromatography (LC) combined with atmospheric pressure chemical ionization mass spectrometry was used to identify phase I and II metabolites of the drug BW 1370U87 in dog and human urine. Additional analysis of individual high-performance liquid chroma... |
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Measurement of myo-inositol in diabetic sera by GC/MS/SIM using n-butylboronate derivatives.
Clin. Chim. Acta 176(2) , 207-12, (1988)
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A transition-state-analog inhibitor influences zinc-binding by Aeromonas aminopeptidase.
Biochem. Biophys. Res. Commun. 130(3) , 1154-60, (1985) The transition-state-analog inhibitor, 1-butaneboronic acid, markedly enhances the uptake of one g-atom of Zn2+ ions from a metal ion buffer system by Zn-depleted Aeromonas aminopeptidase. In contrast, a substrate-analog inhibitor, n-valeramide, does not pert... |
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15 beta-hydroxysteroids (Part III). Steroids of the human perinatal period: the synthesis of 3 beta, 15 beta, 17 alpha-trihydroxy-5-pregnen-20-one. Application of n-butyl boronic acid protection of a 17,20-glycol.
Steroids 61(1) , 11-7, (1996) We report the synthesis of 3 beta,15 beta,17 alpha-trihydroxy-5-pregnen-20- one (1) from 3 beta,15 beta-dihydroxy-5,16-pregnadien-20-one (11) in 7 steps using boronate derivatives as a means of protecting the 17,20-glycol side-chain of steroid intermediates. ... |
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Inhibition studies of soybean (Glycine max) urease with heavy metals, sodium salts of mineral acids, boric acid, and boronic acids.
J. Enzyme Inhib. Med. Chem. 25(5) , 646-52, (2010) Various inhibitors were tested for their inhibitory effects on soybean urease. The K(i) values for boric acid, 4-bromophenylboronic acid, butylboronic acid, and phenylboronic acid were 0.20 +/- 0.05 mM, 0.22 +/- 0.04 mM, 1.50 +/- 0.10 mM, and 2.00 +/- 0.11 mM... |
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[Gas chromatographic separation of the diastereomers of labetalol as n-butylboronate].
Yakugaku Zasshi 103(9) , 974-8, (1983)
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Beta2-adrenergic agonist residues: simultaneous methyl- and butylboronic derivatization for confirmatory analysis by gas chromatography-mass spectrometry.
J. Chromatogr. B. Biomed. Sci. Appl. 716(1-2) , 366-70, (1998) A derivatization procedure for confirmatory residue analysis of beta2-agonists is described. Methyl (MBA) and butyl (BBA) boronic acids are simultaneously used for the derivatization of tulobuterol, mabuterol, mapenterol, salbutamol, clenproperol, clenbuterol... |
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Measurement of inositol in uremic serum by selected ion monitoring.
Jpn. J. Med. 27(1) , 29-33, (1988) A highly sensitive and specific quantitative assay for inositol in serum has been developed. Uremic serum, to which hexahydroxybenzene as an internal standard was added, was deproteined with trichloroacetate. The supernatant aqueous phase was taken after lipi... |