Methscopolamine (bromide)
Methscopolamine (bromide) structure
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Common Name | Methscopolamine (bromide) | ||
|---|---|---|---|---|
| CAS Number | 155-41-9 | Molecular Weight | 398.292 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H24BrNO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo.
Biochem. Pharmacol. 90(3) , 307-19, (2014) Activation of G protein-coupled receptors involves major conformational changes of the receptor protein ranging from the extracellular transmitter binding site to the intracellular G protein binding surface. GPCRs such as the muscarinic acetylcholine receptor... |
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The development of anticholinergics in the management of COPD.
Int. J. Chron. Obstruct. Pulmon. Dis. 2(1) , 33-40, (2007) Anticholinergics have been used to treat obstructive respiratory disease for many years from historical preparations of the deadly nightshade genus, to the more recent developments ofipratropium, oxitropium, and tiotropium. The medical treatment of airways ob... |
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Effects of scopolamine and nicotine on human rapid information processing performance.
Psychopharmacology 82(3) , 147-50, (1984) In the first experiment, after a 10-min baseline test on a rapid information processing task, subjects received oral doses of either placebo, methscopolamine 1.2 mg, scopolamine 0.6 mg or scopolamine 1.2 mg, and 1 h later performed the task again for a 20-min... |
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The central effects of scopolamine in man.
Biol. Psychiatry 3(4) , 347-55, (1971)
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Muscarinic receptors and their mRNAs in type 2 Goto-Kakizaki diabetic rat prostate.
Prostate 70(14) , 1533-9, (2010) As increasing evidence is pointing towards the relationship between diabetes and benign prostatic hyperplasia/lower urinary tract symptoms, we investigated the pharmacological properties and gene expressions of the muscarinic receptors in type 2 diabetes rat ... |
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Central and peripheral des-acyl ghrelin regulates body temperature in rats.
Biochem. Biophys. Res. Commun. 430(1) , 278-83, (2013) In the present study using rats, we demonstrated that central and peripheral administration of des-acyl ghrelin induced a decrease in the surface temperature of the back, and an increase in the surface temperature of the tail, although the effect of periphera... |
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Comparison of subcellular distribution and functions between exogenous and endogenous M1 muscarinic acetylcholine receptors.
Life Sci. 93(1) , 17-23, (2013) Recombinant systems have been used for evaluating the properties of G-protein-coupled receptors (GPCRs) on the assumption of cell surface expression. However, many GPCRs, including muscarinic acetylcholine receptors (mAChRs), have also been reported to be dis... |
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Assessment of novel muscarinic acetylcholine receptors in rat cerebral cortex by a tissue segment binding method.
J. Pharmacol. Sci. 112(4) , 444-51, (2010) Muscarinic acetylcholine receptors (mAChRs) of rat cerebral cortex were evaluated using a tissue segment radioligand binding assay. [(3)H]-Quinuclidinyl benzilate (QNB, a hydrophobic ligand) specifically bound to mAChRs in the cortex segments. The total mAChR... |
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Characterization of muscarinic receptors in the human bladder mucosa: direct quantification of subtypes using 4-DAMP mustard.
Urology 78(3) , 721.e7-721.e12, (2011) To characterize pharmacologically relevant muscarinic receptors in the human bladder mucosa and detrusor muscle using radioligand binding assays with [N-methyl-3H]scopolamine methyl chloride ([3H]NMS) and 4-DAMP mustard.Muscarinic receptors in homogenates of ... |