3-Methoxybenzoic acid

3-Methoxybenzoic acid Structure
3-Methoxybenzoic acid structure
Common Name 3-Methoxybenzoic acid
CAS Number 586-38-9 Molecular Weight 152.147
Density 1.2±0.1 g/cm3 Boiling Point 308.0±0.0 °C at 760 mmHg
Molecular Formula C8H8O3 Melting Point 105-107 °C(lit.)
MSDS Chinese USA Flash Point 123.3±13.3 °C
Symbol GHS07
GHS07
Signal Word Warning

3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Bioorg. Med. Chem. 15 , 2006-15, (2007)

Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-quinones. Inhibition of PO may provide a basis for novel env...

Characterization of the superinduction of the c-myc proto-oncogene in fibroblasts by benzamide derivatives.

Mol. Cell Biochem. 124(2) , 175-81, (1993)

In mouse fibroblasts stimulated from quiescence into proliferation by serum the induction of expression of the c-myc proto-oncogene is strongly stimulated by 3-methoxybenzamide. Similar superinduction effects are seen with related compounds such as 3-aminoben...

Mass spectrometric behavior of phenolic acids standards and their analysis in the plant samples with LC/ESI/MS system.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 21-7, (2014)

Liquid chromatography coupled to mass spectrometry (MS) with electrospray ionization (ESI) is one of analytical techniques to obtain accurate results of low molecular weight aromatic compounds in biological samples of different origin. The interpretations of ...

The versatility of the fungal cytochrome P450 monooxygenase system is instrumental in xenobiotic detoxification.

Mol. Microbiol. 81(5) , 1374-89, (2011)

Cytochromes P450 (CYPs) catalyse diverse reactions and are key enzymes in fungal primary and secondary metabolism, and xenobiotic detoxification. CYP enzymatic properties and substrate specificity determine the reaction outcome. However, CYP-mediated reaction...

Comparative functional characterization of a novel benzoate hydroxylase cytochrome P450 of Fusarium oxysporum.

Enzyme Microb. Technol. 70 , 58-65, (2015)

FoCYP53A19, a novel cytochrome P450 capable of performing benzoate hydroxylation, was identified and characterized from the ascomycete Fusarium oxysporum f.sp. lycopersici. Comparative functional analysis of FoCYP53A19 with the heterologous and homologous cyt...

Hepatic microsomal thiol methyltransferase is involved in stereoselective methylation of pharmacologically active metabolite of prasugrel.

Drug Metab. Dispos. 42(7) , 1138-45, (2014)

Prasugrel, a thienopyridine antiplatelet drug, is converted in animals and humans to the pharmacologically active metabolite R-138727 [(2Z)-{1-[(1RS)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene}ethanoic acid], which has two chir...

Utilization of methoxylated benzoates and formation of intermediates by Desulfotomaculum thermobenzoicum in the presence or absence of sulfate.

Arch. Microbiol. 157(3) , 209-12, (1992)

Desulfotomaculum thermobenzoicum strain TSB (DSM 6193) was found to utilize some methoxylated benzoates as carbon and energy source with or without sulfate. 3- or 4-Methoxybenzoate, vanillate (4-hydroxy-3-methoxybenzoate), syringate (3,5-dimethoxy-4-hydroxybe...

[Synthesis and characterization of complex of NdL3.2H2O].

Guang Pu Xue Yu Guang Pu Fen Xi 20(3) , 322-3, (2000)

The binary solid complexes using rare earth ion Nd3+ with the ligand L (L = O-chorophenoxyacetic acid and 3-methoxybenzoic acid) has been synthesized in this work. The chemical formula of the complex was determined to be NdL3.2H2O by elemental analysis. The c...

Effects of solute characteristics and concentration on a lyotropic liquid crystal: solute-induced phase change.

Pharm. Res. 10(5) , 737-42, (1993)

We investigated the effects of increased concentrations of the solutes, salicylic acid, benzoic acid, and o-, m-, and p-methoxy benzoic acids, on the anisotropic properties of a liquid crystal solvent. The lamellar liquid crystal was composed of 37% polyoxyet...

The trans-anethole degradation pathway in an Arthrobacter sp.

J. Biol. Chem. 277(14) , 11866-72, (2002)

A bacterial strain (TA13) capable of utilizing t-anethole as the sole carbon source was isolated from soil. The strain was identified as Arthrobacter aurescens based on its 16 S rRNA gene sequence. Key steps of the degradation pathway of t-anethole were ident...